2026

PSMC-FAC: A Statistical Framework for Correcting Loss of Heterozygosity in Low-Coverage Genomic Demographic Inference

Iglesias-Santos, F., Nieto, A., Casillas, S., Barbadilla, A. & Sarabia, C., 1 Mar 2026, In: Preprints. (preprint)

2025

Footprints of Worldwide Adaptation in Structured Populations of Drosophila melanogaster Through the Expanded DEST 2.0 Genomic Resource

Nunez, J. C. B., Coronado-Zamora, M., Gautier, M., Kapun, M., Steindl, S., Ometto, L., Hoedjes, K., Beets, J., Wiberg, R. A. W., Mazzeo, G. R., Bass, D. J., Radionov, D., Kozeretska, I., Zinchenko, M., Protsenko, O., Serga, S. V., Amor-Jimenez, C., Casillas, S., Sánchez-Gracia, A. & Patenkovic, A. & 82 others, , 18 Aug 2025, In: Molecular Biology and Evolution. 8, msaf132.

2024

An efficient and robust ABC approach to infer the rate and strength of adaptation

Casillas, S.Barbadilla, A., Uricchio, L. & Enard, D., 14 Feb 2024, In: G3: Genes, Genomes, Genetics. 14, 23 p.

Multiple Genomic Landscapes of Recombination and Genomic Divergence in Wild Populations of House Mice—The Role of Chromosomal Fusions and Prdm9

Marín-García, C., Álvarez-González, L., Marín-Gual, L., Casillas, S., Picón, J., Yam, K., Garcias-Ramis, M. M., Vara, C., Ventura, J., Ruiz-Herrera, A. & Larracuente, A. (Editor), 21 Mar 2024, In: Molecular Biology and Evolution. 41, 4, 16 p., msae063.

2023

An efficient and robust ABC approach to infer the rate and strength of adaptation

Murga-Moreno, J., Casillas, S., Barbadilla, A., Uricchio, L. & Enard, D., 28 Sept 2023, 39 p. (preprint)

2022

impMKT: the imputed McDonald and Kreitman test, a straightforward correction that significantly increases the evidence of positive selection of the McDonald and Kreitman test at the gene level

Murga-Moreno, J., Coronado-Zamora, M.Casillas, S. & Barbadilla, A., Oct 2022, In: G3: Genes, Genomes, Genetics. 12, 10, 14 p., jkac206.

PopHumanVar : an interactive application for the functional characterization and prioritization of adaptive genomic variants in humans

Colomer-Vilaplana, A., Murga-Moreno, J., Canalda-Baltrons, A., Inserte, C., Soto, D., Coronado-Zamora, M.Barbadilla, A. & Casillas, S., 2022, In: Nucleic acids research. 50, D1, p. D1069-D1076 8 p.

2021

Drosophila Evolution over Space and Time (DEST) – A New Population Genomics Resource

Glaser-Schmitt, A., Jelic, M., Gallardo-Jiménez, F. D., Puerma, E., Tauber, E., Schou, M. F., Fabian, D. K., Ullastres, A., Kapun, M., Espinosa-Jimenez, M. L., Bogaerts-Márquez, M., Merenciano, M., Outten, J., Rota-Stabelli, O., Buendía-Ruíz, A. J., Wheat, C. W., Guio, L., Paris, M., Patenkovic, A. & Lazzaro, B. P. & 31 others, , 9 Dec 2021, In: Molecular Biology and Evolution. 38, 12, p. 5782-5805 24 p.

2020

Germline de novo mutation rates on exons versus introns in humans

Rodriguez-Galindo, M., Casillas, S., Weghorn, D. & Barbadilla, A., 2020, In: Nature Communications. 11

2019

Genome-Wide Patterns of Sequence Divergence of Protein-Coding Genes between Drosophila buzzatii and D. mojavensis

Guillén, Y., Casillas, S. & Ruiz, A., 7 Jan 2019, In: Journal of Heredity. 110, 1, p. 92-101 10 p.

IMKT: The integrative McDonald and Kreitman test

Murga-Moreno, J., Coronado-Zamora, M., Hervas, S., Casillas, S. & Barbadilla, A., 1 Jul 2019, In: Nucleic acids research. 47, W1, p. W283-W288

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

RELISH Consortium, 2019, In: Database. 2019, p. 1-67 67 p.

PopHumanScan: The online catalog of human genome adaptation

Murga-Moreno, J., Coronado-Zamora, M., Bodelón, A., Barbadilla, A. & Casillas, S., 8 Jan 2019, In: Nucleic Acids Research. 47, D1, p. D1080-D1089

2018

PopHuman: The human population genomics browser

Casillas, S., Mulet, R., Villegas-Mirón, P., Hervas, S., Sanz, E., Velasco, D., Bertranpetit, J., Laayouni, H. & Barbadilla, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D1003-D1010 8 p.

2017

Molecular population genetics

Casillas, S. & Barbadilla, A., Mar 2017, In: Genetics. 205, 3, p. 1003-1035 33 p.

PopFly: the Drosophila population genomics browser

Hervas, S., Sanz, E., Casillas, S., Pool, J. E. & Barbadilla, A., 1 Sept 2017, In: Bioinformatics (Oxford, England). 33, 17, p. 2779-2780 2 p.

2014

Genomics of ecological adaptation in cactophilic Drosophila

Guillén, Y., Rius, N., Delprat, A., Williford, A., Muyas, F., Puig, M.Casillas, S., Ràmia, M., Egea, R., Negre, B., Mir, G., Camps, J., Moncunill, V., Ruiz-Ruano, F. J., Cabrero, J., De Lima, L. G., Dias, G. B., Ruiz, J. C., Kapusta, A. & Garcia-Mas, J. & 10 others, , 27 Dec 2014, In: Genome Biology and Evolution. 7, 1, p. 349-366 18 p.

2012

PopDrowser: The population drosophila browser

Ràmia, M., Librado, P., Casillas, S., Rozas, J. & Barbadilla, A., Feb 2012, In: Bioinformatics. 28, 4, p. 595-596 2 p., btr691.

The Drosophila melanogaster Genetic Reference Panel

Mackay, T., Richards, S., Stone, E., Barbadilla, A., Ayroles, J., Zhu, D., Casillas, S., Han, Y., Magwire, M. & Cridland, J. M., 1 Feb 2012, In: Nature. 482, 7384, p. 173-178

2011

MASISH: A database for gene expression in maize seeds

Miquel, M., López-Ribera, I., Ràmia, M., Casillas, S.Barbadilla, A. & Vicient, C. M., Feb 2011, In: Bioinformatics. 27, 3, p. 435-436 2 p., btq654.

2008

Standard and generalized McDonald-Kreitman test: a website to detect selection by comparing different classes of DNA sites.

Egea, R., Casillas, S. & Barbadilla, A., 1 Jul 2008, In: Nucleic acids research. 36, p. W157-162 8 p.

2007

Drosophila polymorphism database (DPDB) a portal for nucleotide polymorphism in Drosophila

Casillas, S., Egea, R., Petit, N., Bergman, C. M. & Barbadilla, A., 2007, In: Fly. 1, 4, p. 205-211 7 p.

MamPol: A database of nucleotide polymorphism in the Mammalia class

Egea, R., Casillas, S., Fernández, E., Senar, M. À. & Barbadilla, A., Jan 2007, In: Nucleic acids research. 35, SUPPL. 1, p. D624-D629

Protein polymorphism is negatively correlated with conservation of intronic sequences and complexity of expression patterns in Drosophila melanogaster

Petit, N., Casillas, S., Ruiz, A. & Barbadilla, A., May 2007, In: Journal of Molecular Evolution. 64, 5, p. 511-518 8 p.

Purifying selection maintains highly conserved noncoding sequences in Drosophila

Casillas, S.Barbadilla, A. & Bergman, C. M., Oct 2007, In: Molecular Biology and Evolution. 24, 10, p. 2222-2234 13 p.

2006

Fast sequence evolution of Hox and Hox-derived genes in the genus Drosophila

Casillas, S., Negre, B., Barbadilla, A. & Ruiz, A., 12 Dec 2006, In: BMC Evolutionary Biology. 6, 15 p., 106.

PDA v.2: Improving the exploration and estimation of nucleotide polymorphism in large datasets of heterogeneous DNA

Casillas, S. & Barbadilla, A., Jul 2006, In: Nucleic Acids Research. 34, WEB. SERV. ISS., p. W632-W634 3 p.

2005

Conservation of regulatory sequences and gene expression patterns in the disintegrating Drosophila Hox gene complex

Negre, B., Casillas, S., Suzanne, M., Sánchez-Herrero, E., Akam, M., Nefedov, M., Barbadilla, A., De Jong, P. & Ruiz, A., 1 May 2005, In: Genome Research. 15, 5, p. 692-700 9 p.

DPDB: A database for the storage, representation and analysis of polymorphism in the Drosophila genus

Casillas, S., Petit, N. & Barbadilla, A., 1 Sept 2005, In: Bioinformatics. 21, SUPPL. 2, p. ii26-ii30 5 p.

2004

PDA: A pipeline to explore and estimate polymorphism in large DNA databases

Casillas, S. & Barbadilla, A., 1 Jul 2004, In: Nucleic Acids Research. 32, p. W166-W169 4 p.