Table 4. Genes whose alkaline pH induction is reduced by calcineurin deficiency. Timing of the response is defined in the main text. Numbers indicate the induction level for each strain at the indicated timing(s). ND, not dependent, WD, weakly dependent, SD, strongly dependent, TD, totally dependent. See text for details.

 

 

 

ORF

Timing

wt

cnb1

calcineurin dependence

crz1

Crz1 dependence

CDRE motif

 

 

 

 

 

 

 

 

YAL005C (SSA1)

E/I

2.2/2.2

1.1/0.8

SD/SD

1.6/1.7

SD/SD

0

YBR016W

E/I

2.7/2.7

1.5/1.8

WD/WD

1.0/1.1

WD/WD

0

YBR287W

E

3.8

1.9

SD

2.0

SD

1

YBR296C (PHO89)

E

4.9

0.7

TD

1.0

TD

2

YCL020W

E

2.6

1.1

TD

0.9

TD

0

YDR077W (SED1)

E

2.7

1.4

WD

1.7

WD

0

YDR372C (VPS74)

E

2.9

1.2

SD

1.3

SD

1

YEL060C (PRB1)

E

9.1

3.8

SD

4.1

SD

2

YER062C (HOR2)

E/I

2.8/2.8

1.0/1.3

TD/TD

2.5/1.5

ND/WD

0

YGL253W (HXK2)

E

4.1

1.3

SD

1.9

SD

0

YGR032W (GSC2)

I

2.5

0.8

TD

0.9

TD

2

YGR157W (CHO2)

E

2.9

1.3

TD

1.1

TD

0

YGR211W (ZPR1)

E

2.8

1.3

TD

2.0

ND

0

YJR032W (CPR7)

L

3.2

1.3

SD

1.2

TD

0

YKL043W (PHD1)

E

4.1

2.2

WD

2.4

WD

0

YKL152C (GPM1)

E

2.2

1.1

SD

1.0

SD

1

YLR012C

L

2.1

1.0

SD

1.0

SD

0

YLR089C (ALT1)

E

3.7

2.0

WD

2.5

ND

0

YLR142W (PUT1)

E

2.6

1.2

TD

2.4

ND

1

YMR011W (HXT2)

E

21.1

9.7

SD

15.3

ND

0

YMR083W (ADH3)

E

2.2

1.1

SD

0.9

SD

0

YNL160W (YGP1)

E

2.7

1.5

WD

1.1

TD

1

YNL208W

E

3.1

1.8

WD

2.7

ND

0

YOR049C (RSB1)

E

3.3

1.2

TD

2.5

ND

0

YOR220W

E

4.5

1.9

SD

3.0

WD

2

YPL057C (SUR1)

E

3.2

1.4

SD

1.9

WD

2

YPL154C (PEP4)

I

3.9

1.6

SD

2.2

WD

1