{"id":208,"date":"2011-02-28T15:57:56","date_gmt":"2011-02-28T13:57:56","guid":{"rendered":"https:\/\/webs.uab.cat\/gbml\/serrano-table-1\/"},"modified":"2011-02-28T15:57:56","modified_gmt":"2011-02-28T13:57:56","slug":"serrano-table-1","status":"publish","type":"page","link":"https:\/\/webs.uab.cat\/gbml\/ca\/serrano-table-1\/","title":{"rendered":"Serrano Table 1"},"content":{"rendered":"\n\n\n\n
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Serrano R, Bernal D, Simon E, Arino J. (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J. Biol. Chem<\/strong>. 279, 19698-19704.<\/a><\/p>\n<\/td>\n<\/tr>\n

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Table 1.- Mutations that results in growth defect under alkaline conditions.<\/strong> Numbers in parentheses indicates the level of alkaline sensitivity (being 1 the highest sensitivity). Genes in bold type correspond to those identify in a recent report (11) as conferring a fitness defect when deleted. For details see the main text.<\/p>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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Function<\/h3>\n<\/td>\n

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Alkaline pH sensitive mutants<\/strong><\/h1>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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 <\/p>\n<\/td>\n<\/tr>\n

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Vacuole organization and biogenesis<\/span><\/strong><\/h1>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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CUP5 (1), TFP1 (1), VMA2 (1), VMA22 (1), VMA4 (1), VMA5 (1), VMA6 (1), VMA7 (1), CWH36 (1), VMA21 (2), PEP3 (2), PEP5 (2), PPA1 (2), TFP3 (2), VMA13 (2), VPS16 (2), VPS33 (2), VPS34 (2), ARP5 (3), VPS15 (3), FAB1 (4), PEP7 (4), VMA8 (4), VPS65 (5)<\/em><\/p>\n<\/td>\n<\/tr>\n

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Transport in other organelles<\/span><\/strong><\/h1>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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GCS1 (3)<\/em><\/strong>, SEC22 (3), DRS2 (3)<\/strong>, VPS20 (4), GLO3 (4), COG8 (4), SYS1 (4)<\/strong><\/em><\/p>\n<\/td>\n<\/tr>\n

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Metal ion homeostasis<\/span><\/strong><\/h1>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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CTR1 (1), RCS1 (1), SOD1 (1), LYS7 (2)<\/strong>, SOD2 (2), CCC2 (4)<\/strong>, FET3 (4)<\/strong>, PMR1 (4)<\/em><\/p>\n<\/td>\n<\/tr>\n

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Metabolism<\/span><\/strong><\/h1>\n<\/td>\n<\/tr>\n

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Aminoacid<\/strong> metabolism<\/strong><\/p>\n

Lipid metabolism<\/h4>\n

Phosphate metabolism<\/strong><\/p>\n<\/td>\n

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 <\/p>\n<\/td>\n

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GLY1 (1), PHO2 (1), PRO1 (1), CYS3 (3), ARO2 (4)<\/strong>, ILV1 (4)<\/strong>, TYR1 (5)<\/em><\/p>\n

ERG2 (2)<\/em><\/strong>, ERG6 (2), ARV1 (3), BTS1 (3), AGP2 (4), DAP1 (4), FEN1 (4), MGA2 (4)<\/strong><\/em><\/p>\n

PHO4 (2)<\/em><\/strong>, PHO81 (2), PHO85 (3)<\/em><\/p>\n<\/td>\n<\/tr>\n

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Protein biosynthesis<\/span><\/strong><\/h2>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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TEF4 (3), FES1 (4), HCR1 (4), RPL13B (4), RPL27A (4)<\/em><\/p>\n<\/td>\n<\/tr>\n

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Cell polarity, cell wall organization and biogenesis<\/span><\/strong><\/h2>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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RHO4 (1), BUD25 (1), BEM1 (2), GAS1 (2), SLT2 (2)<\/strong>, BCK1 (3)<\/strong>, BEM4 (4), CNB1 (5)<\/strong><\/em><\/p>\n<\/td>\n<\/tr>\n

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Chromatin modification, architecture & transcription<\/span><\/strong><\/h2>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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SWI3 (1), BUR2 (3), DAL81 (3)<\/strong>, GCN5 (3), HTZ1 (3), REF2 (3), REG1 (3), RPB9 (3), SPT20 (3), SSN8 (3), UME6 (3), ADA2 (4), KEM1 (4), MED2 (4), SPC72 (4), SRB5 (4), SWI4 (4), TOP1 (4)<\/strong>, MRS1 (5)<\/em><\/p>\n<\/td>\n<\/tr>\n

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Others<\/span><\/strong><\/h2>\n<\/td>\n<\/tr>\n

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 <\/p>\n<\/td>\n

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PHO86 (1)<\/em><\/strong>, KEX2 (1), RIB4 (1), DIA2 (2), SPS1 (2), FYV6 (3), MAP1 (3), TPD3 (3), ADE12 (4), ATP1 (4), ATP11 (4), NEM1 (4), PTC1 (4), URE2 (4)<\/strong>, ZWF1 (4), COX16 (5), RIB1 (5), SCP160 (5)<\/strong><\/em><\/p>\n<\/td>\n<\/tr>\n

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Unknown<\/span><\/strong><\/h2>\n<\/td>\n<\/tr>\n

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 <\/em><\/p>\n<\/td>\n

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YEL045C (1), YKL118W (1), YOR331C (1), YJL175W (3), HUR1 (4), ILM1 (4), PKR1 (4),<\/strong> YLR358C (4), YJR018W (5), YOR251C (5), YOR305W (5)<\/em><\/p>\n<\/td>\n<\/tr>\n

<\/td>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Serrano R, Bernal D, Simon E, Arino J. (2004) Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. J. Biol. Chem. 279, 19698-19704.       Table 1.- Mutations that results in growth defect under alkaline conditions. Numbers in parentheses indicates the level of alkaline sensitivity […]<\/p>\n","protected":false},"author":20,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-208","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/pages\/208","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/comments?post=208"}],"version-history":[{"count":0,"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/pages\/208\/revisions"}],"wp:attachment":[{"href":"https:\/\/webs.uab.cat\/gbml\/ca\/wp-json\/wp\/v2\/media?parent=208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}