2026

  • Barata-Antunes C, Warmerdam M, de Hulster E, Ribeiro, I. P., Cardoso, C., Leite, B., Casal, M., Gerós, H., Pronk, J., Ariño, J., Mans, R., & Paiva, S. Endocytosis of the Saccharomyces cerevisiae Jen1 monocarboxylate-proton symporter under mildly alkaline conditions: a mechanism to prevent metabolite loss?. Microb Cell Fact. 2026;25(1):87. doi:10.1186/s12934-026-02955-6
  • Albacar M, Casamayor A, Wang R, Ariño J, González A. The transcriptional response to environmental alkalization involves both Komagataella phaffii Pho4 transcription factors. Microb Cell Fact. in press doi:10.1186/s12934-026-03054-2
  • Albacar M, González A, Wang R, Casamayor A, Ariño J. Komagataella phaffii Encodes Two Functional Pho4 Transcription Factors. Int J Mol Sci. 2026;27(15):6561. Published 2026 Jul 23. doi:10.3390/ijms27156561

2025

  • Zekhnini A, Casamayor A, Ariño J. Combinatorial Alkali-Responsive Hybrid Promoters as Tools for Heterologous Protein Expression in Saccharomyces cerevisiae. Microb Biotechnol. 2025;18(9):e70213. doi:10.1111/1751-7915.70213
  • Albacar M, Casamayor A, Zekhnini A, Schmidt A, González A, Ariño J. Signaling pathways contributing to the transcriptional response to alkalinization in Komagataella phaffii: role of the transcription factors Crz1 and Rim101. Scientific Reports. 2025;15(1):35841. doi:10.1038/s41598-025-20192-6
  • Ariño J. Transcriptional Responses to Alkaline pH Across Fungi: Common and Differential Features, and Biotechnological Applications. Int J Mol Sci. 2025;26(23):11450. doi:10.3390/ijms262311450
  • Gomes-Gonçalves A, Van Genechten W, Ataíde P, Barata-Antunes, C., Ghasemi, F., Casal, M., Teixeira, M. C., Ariño, J., Brown, A. J. P., Van Dijck, P., & Paiva. Lactic Acid Influences Iron Assimilation by a Fungal Pathogen via the Iron Reductive Uptake Pathway. Microbiologyopen. 2025;14(6):e70167. doi:10.1002/mbo3.70167

2024

  • Harnessing alkaline-pH regulatable promoters for efficient methanol-free expression of enzymes of industrial interest in Komagataella phaffii (2024) Microbial Cell Factories 23(1): 99. doi: 10.1186/s12934-024-02362-9

2023

  • Bravo-Alonso, I.; Morin, M.; Arribas-Carreira, L.; Álvarez, M.; Pedrón-Giner, C.; Soletto, L.; Santolaria, C.; Ramón-Maiques, S.; Ugarte, M.; Rodríguez-Pombo, P.; Ariño, J.; Moreno-Pelayo, M.A.; Pérez, B. (2023) Pathogenic variants of the coenzyme A biosynthesis-associated enzyme phosphopantothenoylcysteine decarboxylase (PPCDC) cause autosomal-recessive dilated cardiomyopathy. Journal of Inherited Metabolic Disease. 46(2):261-272. doi: 10.1002/jimd.12584
  • Albacar, M; Zekhnini, A.; Pérez-Valle, J.; Martínez, J.L., Casamayor, A.; Ariño, J. (2023) Transcriptomic profiling of the yeast Komagataella phaffii in response to environmental alkalinization. Microbial Cell Factories. 22(1):63. doi: 10.1186/s12934-023-02074-6.

2022

  • Casamayor A, Ariño J. Fungal Hal3 (and Its Close Relative Cab3) as Moonlighting Proteins. J Fungi (Basel). 2022;8(10):1066. doi:10.3390/jof8101066
  • Santolaria C, Velázquez D, Albacar M, Casamayor A, Ariño J. Functional mapping of the N-terminal region of the yeast moonlighting protein Sis2/Hal3 reveals crucial residues for Ppz1 regulation. FEBS J. 2022;289(23):7500-7518. doi:10.1111/febs.16572
  • Casamayor A, Ariño J. When Phosphatases Go Mad: The Molecular Basis for Toxicity of Yeast Ppz1. Int J Mol Sci. 2022;23(8):4304. doi:10.3390/ijms23084304
  • Albacar M, Velázquez D, Casamayor A, Ariño J. The toxic effects of yeast Ppz1 phosphatase are counteracted by subcellular relocalization mediated by its regulatory subunit Hal3. FEBS Lett. 2022;596(12):1556-1566. doi:10.1002/1873-3468.14330
  • Casamayor A, Velázquez D, Santolaria C,  Albacar, M., Rasmussen, M. I., Højrup, P., & Ariño, J. Comparative Analysis of Type 1 and Type Z Protein Phosphatases Reveals D615 as a Key Residue for Ppz1 Regulation. Int J Mol Sci. 2022;23(3):1327. Published 2022 Jan 25. doi:10.3390/ijms23031327

2021

  • Flores CL, Ariño J, Gancedo C. The N-Acetylglucosamine Kinase from Yarrowia lipolytica Is a Moonlighting Protein. Int J Mol Sci. 2021;22(23):13109. doi:10.3390/ijms222313109
  • Albacar M, Sacka L, Calafí C, Velázquez, D., Casamayor, A., Ariño, J., & Zimmermannova, O. The Toxic Effects of Ppz1 Overexpression Involve Nha1-Mediated Deregulation of K+ and H+ Homeostasis. J Fungi (Basel). 2021;7(12):1010. doi:10.3390/jof71210102023

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