Research Lines
- Cellular and molecular mechanisms implicated in motoneuron degenerative diseases in experimental models. Neuroprotective strategies based on gene and pharmacological therapy.
- Cell therapy by transplantation of mesenchymal stem cells and neural stem cells for the repair of spinal cord injuries and motoneuron degenerative diseases.
- Repair of spinal root injuries and pharmacological neuroprotection.
- Etiopathogenic role of lipid mediators and modulators of the neuroinflammatory response in neurodegeneration induced by central nervous system lesions.
- Activity-dependent therapies for enhancing axonal regeneration and functional recovery after peripheral nerve lesions and for preventing neuropathic pain.
- Physiopathologic mechanisms in neuropathic pain induced by nerve and spinal cord lesions.
- Epigenetic therapy to enhance functional outcome after traumatic injuries of the nervous system.
- Study of etiopathogenic mechanisms and potential neuroprotective treatments in peripheral neuropathies induced by diabetes and by antitumoral agents.
- Neuromodulation of neural plasticity for promoting functional restitution in spinal cord injuries.
- Design and evaluation of neural interfaces for the development of neuroprostheses applied to neurorehabilitation. Study of new intraneural electrodes for the selective stimulation and recording of neural activity.
- Study of cellular and molecular mechanisms involved in demyelinating diseases.
