Design of tumor-targeted nanostructured venoms for the treatment of CXCR4+ human neoplasias (VENOM4CANCER), Coordinator A. Villaverde. Intramural CIBER. 2018-25.
Design and implementation of a novel protein-based nanobiotechnological platform for the remote delivery of tumor-targeted antitumoral drugs (NANOREMOTE). Coordinator Esther Vázquez. Intramural CIBER. 2018-25.
Targeted nanoparticle combination for the selective killing of metastasis stem cells and metastasis associated fibroblasts in colorectal cancer (4NANOMETS). Coordinator Ramón Mangues Bafalluy. Intramural CIBER. 2018-25.
Design of protein nanomedicines for the targeted therapy of pancreatic cancer. PANCREATOR. Coordinador Jose Luis Corchero. Intramural CIBER. 2018-25.
Improved colorectal cancer therapy using CXCR4-targeted functional protein nanoparticles with enhanced cytosolic release. NANOSCAPE. Coordinator Ugutz Unzueta. Intramural CIBER. 2019-25.
Humanized nanomedicines selectively killing CXCR4+ cancer cells for Acute Myeloid Leukemia therapy. Fundació La Marató de TV3 201941-31 (30, 31, 32). Coordinator Jordi Sierra. 399178.75 eur.
Functionalization of DNA origami with the T22-GFP-H6 protein for the enhancement of antimetastatic properties (Nanotrojans). Intramural CIBER. 2020-25. Coordinator Ramón Eritja.
Targeted Reinforcement of the innate immune response Against Colorrectal Cancer (TRACC). Coordinador Eloi Parladé. Intramural CIBER. 2021-25.
Site-directed conjugation of multivalent protein ferrrnanomaterial for precision medicines of cancer (NANOLINK). COORDINATOR: Ugutz Unzueta. Intramural CIBER. 2021-25.
Increase of the stability, activity and crossing of biological barriers of recombinant proteins through their vehiculization by EXtracellular vesicles and their PotentiaL biOmedical and industRial usE (EXPLORE-2). COORDINATOR: Ibane Abasolo. Intramural CIBER. 2021-25.
Enzyme MutANts as tools in the quest for improved TheRapies for FAbry disease (MANTRA). COORDINATOR: Neus Ferrer. Intramural CIBER. 2021-25.
Protein delivery system based on non-covalent PEGylation with telodendrimers (TELOprot). COORDINATOR: Miiam Royo. Intramural CIBER. 2021-25.
A long-lasting anti-Covid-19 subcutaneous vaccine through a novel, industrially competitive and biologically safe nanomimetic concept (INVITA). PANDÈMIES 2020. 2020PANDE00003. AGAUR. Generalitat de Catalunya. IP A. Villaverde. 349.000 eur. 13 de Mayo 2021- 12 Noviembre 2022.
MICRO-DEPOSITOS PROTEICOS BIOMIMETICOS COMO UNA PLATAFORMA DE ADMINISTRACION SOSTENIDA DE FARMACOS EN Y A TRAVES DE LA PIEL. PID2020-116174RB-I00. 1/09/2021-31/08/2023. IP A. Villaverde. 121.000 eur.
Membrane biophysics in lysosomal storage disorders for improved therapies (MEMPHYS). COORDINATOR: Pau Gorostiza. Intramural CIBER. 2022-25.
In ovo vaccination of chickens against infectious bursal disease virus using ImmunoStimulatory Protein-Only Microparticles (ISPOM). IP E. Vazquez y A. Villaverde. COORDINATOR: Miquel Nofrarías. AGAUR PRODUCTE 2021 Knowledge Industry. 94.375 eur. 1/09/2022-31/02/2024.
New protein-based nanodrugs for the development of targeted tumor-agnostic therapy. CPP2021-008946. MINISTERIO DE CIENCIA E INNOVACIÓN. Nanoligent SL, Hosp Sant Pau, UAB. 2022-24. 1.357.531,86 eur. IP UAB. E. Vázquez.
Time-sustained therapy of metastatic cancer from secretable nanoparticles. PDC2022-133858-I00. MINISTERIO DE CIENCIA E INNOVACIÓN. 2022-2024. 146.050 €. IP. E. Vázquez.
Grupo de Investigación Consolidado de Catalunya en Biofármacos Innovadores (Grup de Recerca Consolidat de Catalunya en Bio-fàrmacs innovadors). 2021 SGR00092. 2022-2024. A. Villaverde. 40.000 eur.
Estrategias innovadoras para terapia contra células madre tumorales: activando receptores de dopamina con nanopartículas proteicas (PI20/00770). Coordinador: JL Corchero. Instituto de Salud Carlos III (Proyectos de Investigación en Salud, convocatoria 2020 de la Acción Estratégica en Salud). 76.230 €.
Advanced Extracellular Vesicles for Enzyme Replacement Therapy (ADVERT). Coordinador: José Luis Corchero. Instituto de Salud Carlos III-CIBER-BBN (Proyectos de Valorización CIBER-BBN) 2021-2022. 20.000 €.
ARTIFICIAL SECRETION GRANULES FOR REMOTE DELIVERY OF ANTITUMORAL DRUGS. Ministerio de Ciencia e Innovación (PID2019-105416RB-I00) UAB. 2020- 2023. Esther Vázquez. 145.200
Increase of the stability, activity and crossing of biological barriers of recombinant proteins through their vehiculization by EXtracellular vesicles and their PotentiaL biOmedical and industRial usE (EXPLORE-3). Coordinador: Ibane Abasolo. Intramural CIBER. 2023-2024
Tumor extracellular vesicles as nanobeacons for personalized diagnosis of triple negative breast cancer patients (Nanobeacon). Coordinador: Joaquim Seras-Franzoso. Intramural CIBER. 2023-2024
Improved drug delivery systems for enzyme replacement therapies in Fabry disease. Effect of targeting, and protein corona in the efficacy of nanosystems (PEGLyso-2). Coordinador: Ibane Abasolo. Intramural CIBER 2023-2024
Local and Systemic Enzyme Replacement Therapies for Pycnodysostosis (PYCNO-2). Coordinador Ibane Abasolo. Intramural CIBER 2023-2024
Redes reguladoras de quorum sensing en Stenotrophomonas maltophilia como dianas para alternativas terapéuticas a los antibióticos actuales (StenoQS). PID2019-111364RB-I00. IP Xavier Daura y Daniel Yero. 157.300 eur. 2020-2024.
Enzyme propelled nanobots as efficient nanotech platform for bladder cancer therapy. “la Caixa” Banking Foundation Health Research 2021 Call. Ref.: HR21-00208; 01/10/2021-30/09/2024. IP: E. Julián. 997.946,50 €.
Nueva generación de agentes inmunoterapéuticos basados en micobacterias no tuberculosas modificadas (NextNTMdrugs). Ministerio de Ciencia, Innovación y Universidades. PID2021-122331OB-I00; 01/09/2022-31/08/2025. IP: E. Julián. 242.000 €.
NEW FORMULATION OF RECOMBINANT ANTITUMOR VACCINES BASED ON SECRETORY GRANULES FOR SUSTAINED RELEASE (SECRETVAC). MINISTERIO DE CIENCIA E INNOVACIÓN (PID2022-136845OB-I00). UAB. 2023- 2026. IP Antonio Villaverde, Esther Vázquez. 193.750€
PROTEIN-BASED NANOPARTICLES FOR NOSE-TO-BRAIN DELIVERY TO TREAT OBESITY (NANOBESITY) AGAUR (Generalitat de Catalunya) (2023 PROD 00094). Universidad Internacional de Catalunya (UIC), Universidad Autònoma de Barcelona (UAB). 2024-2025. IPs E. Vázquez, A. Villaverde (Coordinator R. Rodríguez). 150.000€.
Time-sustained therapy of metastatic cancer from secretable nanoparticles. MINISTERIO DE CIENCIA E INNOVACIÓN (PDC2022-133858-I00). UAB. 2022-2024. IP E. Vázquez. 146.050 €
New protein-based nanodrugs for the development of targeted tumor-agnostic therapy. MINISTERIO DE CIENCIA E INNOVACIÓN (CPP2021-008946). Nanoligent SL, Universidad Autónoma de Barcelona y Instituto de Investigación del Hospital de La Santa Creu y de San Pau. 2022-2024. IP E. Vázquez (coordinated by Nanoligent). 1.689.076,01 €
In ovo vaccination of chickens against infectious bursal disease virus using ImmunoStimulatory Protein-Only Microparticles (ISPOM). AGAUR (PRODUCTE) (2021 PROD 00196). IRTA, UAB. 2022-2024. IP. E. Vazquez. 94.375 €
BASED NANOPARTICLES FOR NOSE-TO-BRAIN DELIVERY TO TREAT OBESITY (NANOBESITY) AGAUR (Generalitat de Catalunya) (2023 PROD 00094). Universidad Internacional de Catalunya (UIC), Universidad Autònoma de Barcelona (UAB). 2024-2025. IPs E. Vázquez, A. Villaverde (Coordinator R. Rodríguez). 150.000€.
Multifunctional all-protein-based nanoparticles for nose-to-brain delivery. Prestación de servicios en el contexto de una colaboración científica. Universitat Internacional de Catalunya. 2022-2023 IPs: Esther Vázquez, Antonio Villaverde. 3.000 €
Convenio de colaboración entre la Universidad Autónoma de Barcelona y la sociedad Nanoligent S.L. IPs: Esther Vázquez, Antonio Villaverde. 2000€