- Cutando L, Puighermanal E, Castell L, Tarot P, Belle M, Bertaso F, Arango-Lievano M, Ango F, Rubinstein M, Quintana A, Chédotal A, Mameli M, Valjent E. Cerebellar dopamine D2 receptors regulate social behaviors. Nature Neuroscience. 25(7):900-911 (2022)
- Kevin Aguilar K, Comes G, Canal C, Quintana A, Sanz E, Hidalgo J. Microglial response promotes neurodegeneration in the Ndufs4 KO mouse model of Leigh syndrome. GLIA. 70(11):2032-2044. (2022).
- van de Wal M, Adjobo-Hermans M, Keijer J, Schirris T, Homberg J, Wieckowski MR, Grefte S, van Schothorst EM, van Karnebeek C, Quintana A, Werner JH Koopman. Ndufs4 knockout mouse models of Leigh syndrome: pathophysiology and intervention. Brain. 145(1):45-63 (2022)
- Amo-Aparicio J, Garcia-Garcia J, Francos-Quijorna I, Urpi A, Esteve-Codina A, Gut M, Quintana A, and Lopez-Vales R. Interleukin-4 and interleukin-13 induce different metabolic profiles in microglia and macrophages that relate with divergent outcomes after spinal cord injury. Theranostics. 11(20): 9805-9820 (2021)
- Luna-Sánchez M, Bianchi P, Quintana A. Mitochondria-Induced Immune Response as a Trigger for Neurodegeneration: A Pathogen from within. Int. J. Mol. Sci. 2021, 22(16), 8523; https://doi.org/10.3390/ijms22168523
- Puighermanal E, Castell L, Esteve-Codina A, Melser S, Kaganovsky K, Zussy C, Boubaker-Vitre J, Gut M, Rialle S, Kellendonk C, Sanz E, Quintana A, Marsicano G, Martin M, Rubinstein M, Girault JA, Ding JB, Valjent E. Functional and Molecular Heterogeneity of D2R Neurons Along Dorsal Ventral Axis in the Striatum. Nat Commun. 2020 Apr 23;11(1):1957. doi: 10.1038/s41467-020-15716-9.
- Gella A, Prada-Dacasa P, Carrascal M, Urpi A, González-Torres M, Abian J, Sanz E, Quintana A. Mitochondrial Proteome of Affected Glutamatergic Neurons in a Mouse Model of Leigh Syndrome. Front Cell Dev Biol. 2020 Jul 28;8:660. doi: 10.3389/fcell.2020.00660. eCollection 2020.
- Bolea I, Gella A, Sanz E, Prada-Dacasa P, Menardy F, Bard AM, Machuca-Márquez P, Eraso-Pichot A, Mòdol-Caballero G, Navarro X, Kalume F, Quintana A. 2019. Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome. Elife. 8. pii: e47163.
- Sanz E, Bean JC, Carey DP, Quintana A, McKnight GS. 2019. RiboTag: Ribosomal Tagging Strategy to Analyze Cell-Type-Specific mRNA Expression In Vivo. Curr Protoc Neurosci. 88(1):e77.
- Chen B, Hui J, Montgomery KS, Gella A, Bolea I, Sanz E, Palmiter RD, Quintana A. 2017. Loss of Mitochondrial Ndufs4 in Striatal Medium Spiny Neurons Mediates Progressive Motor Impairment in a Mouse Model of Leigh Syndrome. Front Mol Neurosci. 10:265
- Rainwater A, Sanz E, Palmiter RD, Quintana A. 2017. Striatal GPR88 Modulates Foraging Efficiency. J Neurosci. 37(33):7939-7947
- Zimin PI, Woods CB, Quintana A, Ramirez JM, Morgan PG, Sedensky MM. 2016. Glutamatergic Neurotransmission Links Sensitivity to Volatile Anesthetics with Mitochondrial Function. Curr Biol. 26(16):2194-201.
- Padilla SL, Qiu J, Soden ME, Sanz E, Nestor CC, Barker FD, Quintana A, Zweifel LS, Rønnekleiv OK, Kelly MJ, Palmiter RD. 2016. Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state.Nat Neurosci. 19(5):734-41. Cover Article and Featured in News and Views in Nature Neuroscience
- Piroli GG, Manuel AM, Clapper AC, Walla MD, Baatz JE, Palmiter RD, Quintana A, Frizzell N. 2016. Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.Mol Cell Proteomics. 15(2):445-61.
- Sanz E, Quintana A, Deem JD, Steiner RA, Palmiter RD, McKnight GS. 2015. Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors.J Neurosci. 35(14):5549-56
- Liu L, Zhang K, Sandoval H, Yamamoto S, Jaiswal M, Sanz E, Li Z, Hui J, Graham BH, Quintana A, Bellen HJ. 2015. Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration. Cell. 160(1-2):177-90
- Navia B, Ferrer B, Giralt M, Comes G, Carrasco J, Molinero A, Quintana A, Leclerc J, Viollet B, Señarís RM, Hidalgo J. 2014. Interleukin-6 deletion in mice driven by aP2-Cre-ERT2 prevents against high-fat diet-induced gain weight and adiposity in female mice. Acta Physiol. 211(4):585-96.
- Ferrer B, Navia B, Giralt M, Comes G, Carrasco J, Molinero A, Quintana A, Señarís RM, Hidalgo J. 2014. Muscle-specific interleukin-6 deletion influences body weight and body fat in a sex-dependent manner. Brain Behav Immun. pii: S0889-1591(14)00067-1
- Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M. 2013. mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science. 342(6165):1524-8. Featured in Science Express and in Research Highlights in Nature Medicine and Nature Reviews Neurology
- Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD, McKnight GS. 2013. RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo. PLoS ONE 8(6):e66179
- Giralt M, Ramos R, Quintana A, Ferrer B, Erta M, Castro-Freire M, Comes G, Sanz E, Unzeta M, Pifarré P, García A, Campbell IL, Hidalgo J. 2013. Induction of atypical EAE mediated by transgenic production of IL-6 in astrocytes in the absence of systemic IL-6. GLIA 61(4):587-600
- Quintana A, Erta M, Ferrer B, Comes G, Giralt M, Hidalgo J. 2013. Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior. Brain Behav Immun. 27(1):162-173
- Arnett AL, Beutler L, Quintana A, Allen J, Finn E, Palmiter RD, Chamberlain JS. 2013. Heparin-binding influences tissue tropism of AAV1 and AAV6 and increases efficiency of striated muscle transduction in mice. Gene Therapy 20(5):497-503
- Quintana A, Morgan PG, Kruse SE, Palmiter RD, Sedensky MM. 2012 Altered Anesthetic Sensitivity of Mice Lacking Ndufs4, a Subunit of Mitochondrial Complex I. PLoS One 7(8):e42904
- Quintana A, Zanella S, KochH, KruseSE, LeeD,Ramirez JM, Palmiter RD. 2012. Fatal breathing dysfunction in a mouse model of Leigh Syndrome. Journal Clin Invest 122(7):2359-68.
- Quintana A, Sanz E,Wang W, Storey GP, Güler AD, Wanat MJ, Roller BA, La Torre A, Amieux PS, McKnight GS, Bamford NS, Palmiter RD. 2012. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci. 15(11):1547-5. Cover Article and Featured in News and Views in Nature Neuroscience
- Beutler LR, Wanat MJ, Quintana A, Sanz E, Bamford NS, Zweifel LS, Palmiter RD. 2011. Balanced NMDA receptor activity in Dopamine D1 Receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization. Proc Natl Acad Sci USA 108:4206-4211.
- Bruchas MR,Schindler A, Shankar H, Messinger D, Miyatake M, Land BL, Lemos JC, Hagan C, Neumaier J, Quintana A, Palmiter RD, Chavkin C. 2011. Selective p38 (alpha) MAPK deletion in serotonergic neurons produces stress-resilience in models of depression and addiction. Neuron. 71(3):498-511
- Beutler LR, Eldred KC, Quintana A, Keene CD, Rose SE, Postupna N, Montine TJ, Palmiter RD. 2011. Severely impaired learning and altered neuronal morphology in mice lacking NMDA receptors in medium spiny neurons. PLoS One. (11):e28168
- Quintana A, Kruse SE, Kapur RP, Sanz E, Palmiter RD. 2010. Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome. Proc Natl Acad Sci USA. 107:10996-1001. Cover Article
- Quintana A, Müller M, Frausto RF, Ramos R, Getts DR, Sanz E, Hofer MJ, Krauthausen M, King NJ, Hidalgo J, Campbell IL. 2009. Site-specific production of IL-6 in the central nervous system retargets and enhances the inflammatory response in experimental autoimmune encephalomyelitis. J Immunol. 183:2079-88.
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