Emma is the first author of an article published in Nature Communications about the existing differences among neurons expressing dopamine D2 receptors in the striatum. It is an international collaboration in which Albert and Eli also participated. The striatum is a brain region involved in motor control, habit formation, decision-making, motivation and reinforcement, among other […]
We have a new article! Elife published our study in Leigh Syndrome, the most common mitochondrial disease with affectation of the central nervous System. In this disease, there are two brain regions that are particularly compromised: the brainstem (that controls all basic functions that keep us alive) and the basal ganglia, involved in refining motor […]
Wow! what a busy time this past year has been! Many (good) things and (good) news to explain! New members, new papers, exciting science… here you are a picture of the lab just before summer break! First of all, we are glad to announce three! new additions to the lab: Kelsey, Fabien and Patrizia. (disclaimer: […]
Our latest paper is out! In collaboration with the Frizzell lab at the University of South Carolina we have published the article titled: “Succination is increased on select proteins in the brainstem of the Ndufs4 knockout mouse, a model of Leigh syndrome.” in the journal Molecular and Cellular Proteomics. In this paper, we have been able […]
We are really excited that our latest paper, in collaboration with the Bellen lab at Baylor, has been published in the prestigious journal Cell. Our work, titled: Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration, has identified a conserved mechanism that leads to neuronal death after mitochondrial defects. In this study, the Bellen […]