{"id":122,"date":"2023-02-28T22:34:25","date_gmt":"2023-02-28T20:34:25","guid":{"rendered":"https:\/\/webs.uab.cat\/dmrqb\/?page_id=122"},"modified":"2024-01-01T20:49:57","modified_gmt":"2024-01-01T18:49:57","slug":"alejandro-cruz-saez","status":"publish","type":"page","link":"https:\/\/webs.uab.cat\/molbiomed\/alejandro-cruz-saez\/","title":{"rendered":"Alejandro Cruz S\u00e1ez"},"content":{"rendered":"\n
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\"ORCID<\/a>   <\/p>\n\n\n\n

Alejandro Cruz Saez<\/strong> va n\u00e9ixer a Barcelona al 1994. Va cursar el doble grau de F\u00edsica i Qu\u00edmica a la Universitat Aut\u00f2noma de Barcelona durant el per\u00edode 2013-2017. Posteriorment, durant el curs 2017\/2018 va realitzar el m\u00e0ster en Modelitzaci\u00f3 Computacional Atom\u00edstica i Multiescala en F\u00edsica, Qu\u00edmica i Bioqu\u00edmica a la Universitat de Barcelona. Durant els anys 2020\/23 va cursar els estudis de doctorat a la Universitat Aut\u00f2noma de Barcelona on va defensar la tesis titulada: \u201cSimulacions Biomoleculars d\u2019alguns enzims rellevants en processos inflamatoris: 15-LOX, 5-LOX i COX-2. Aplicaci\u00f3 a l\u2019estudi de mecanismes i al disseny d\u2019inhibidors\u201d. <\/p>\n\n\n\n

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Actualment, est\u00e0 realitzant el seu primer any de postdoctorat a la mateixa instituci\u00f3. Els temes de recerca en els que est\u00e0 treballant actualment s\u00f3n l\u2019estudi de mecanismes de reacci\u00f3 catalitzats per enzims i disseny de fotointerruptors amb propietats antiinflamat\u00f2ries.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\u00daltimes Publicacions<\/h2>\n\n\n\n
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ACS Catalysis<\/h1>\n\n\n\n

Theoretical Study of the Arachidonic Acid Conversion into Leukotriene A4<\/sub> Catalyzed by Human 5-Lipoxygenase: Hydroperoxidation and Epoxidation Mechanisms and Arachidonic Acid Active Site Access<\/p>\n\n\n\n

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Llegeix M\u00e9s<\/a> <\/p>\n<\/div>\n\n\n\n

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Molecules<\/h1>\n\n\n\n

Different Structures\u2014Similar Effect: Do Substituted 5-(4-Methoxyphenyl)-1H<\/em>-indoles and 5-(4-Methoxyphenyl)-1H<\/em>-imidazoles Represent a Common Pharmacophore for Substrate Selective Inhibition of Linoleate Oxygenase Activity of ALOX15?<\/p>\n\n\n\n

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Llegeix M\u00e9s<\/a> <\/p>\n<\/div>\n\n\n\n

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Journal of Medicinal Chemistry<\/h1>\n\n\n\n

N<\/em>-Substituted 5-(1H<\/em>-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs: Mechanism of Action<\/p>\n\n\n\n

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Llegeix M\u00e9s<\/a> <\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Alejandro Cruz Saez va n\u00e9ixer a Barcelona al 1994. Va cursar el doble grau de F\u00edsica i Qu\u00edmica a la Universitat Aut\u00f2noma de Barcelona durant el per\u00edode 2013-2017. Posteriorment, durant el curs 2017\/2018 va realitzar el m\u00e0ster en Modelitzaci\u00f3 Computacional Atom\u00edstica i Multiescala en F\u00edsica, Qu\u00edmica i Bioqu\u00edmica a la Universitat de Barcelona. Durant els […]<\/p>\n","protected":false},"author":2580,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-122","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/pages\/122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/users\/2580"}],"replies":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/comments?post=122"}],"version-history":[{"count":19,"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/pages\/122\/revisions"}],"predecessor-version":[{"id":2716,"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/pages\/122\/revisions\/2716"}],"wp:attachment":[{"href":"https:\/\/webs.uab.cat\/molbiomed\/wp-json\/wp\/v2\/media?parent=122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}