Publicaciones científicas – Bases Neurobiològiques i Neurogenètiques dels Trastorns Mentals

2023

Cui, L., Yang, B., Xiao, S., Gao, J., Baud, A., Graham, D., McBride, M., Dominiczak, A., Schafer, S., Lopez Aumatell, R., Mont, C., Fernandez-Teruel, A., Hübner, N., Flint, J., Mott, R., & Huang, L. (2023) Dominance genetic effects are common and are associated with trans-acting and splicing-specific dominance gene expression effects in pigs, rats and mice. Genome Biology, 24(1):215. doi:10.1186/s13059-023-03060-2

Fernández-Teruel A. (2023). From phenomes to genes: phenotype-based strategies in rodents for research on the neurobiological and genetic bases of psychiatric-relevant traits. Current Neuropharmacology, 21(9): 1836–1839. doi:10.2174/1570159X21666230616103143

Fernandez-Teruel, A., Cañete, T., Sampedro-Viana, D., Oliveras, I., Torrubia, R., & Tobeña, A. (2023). Contribution of the Roman rat lines/strains to personality neuroscience: neurobehavioral modeling of internalizing/externalizing psychopathologies. Personality Neuroscience, 6, Article e8. https://doi.org/10.1017/pen.2023.7

Fernández-Teruel A, McNaughton N. (2023) Postencounter freezing during approach-avoidance conflict: the role of the hippocampus. Nature Reviews Neuroscience, 24(7), 451-452. doi: 10.1038/s41583-023-00703-y

Oliveras, I., Cañete, T., Sampedro-Viana, D., RíoÁlamos, C., Tobeña, A., Corda, MG., Giorgi, O., & Fernández-Teruel, A. (2023). Neurobehavioral profiles of six genetically-based rat models of schizophrenia related symptoms. Current Neuropharmacology, 21(9), 1934-1952. https://doi.org/10.2174/1570159×21666230221093644

Peralta-Vallejo, N., Güell-Falgueras, P., Cañete, T., Sampedro-Viana, D., Río-Álamos, C., Oliveras, I., Tobeña, A., & Fernández-Teruel, A. (2023). Schizophreniarelevant social, attentional and cognitive traits in female RHA vs. RLA rats: effects of neonatal handling. Behavioural Brain Research, 459:114762. doi: 10.1016/j.bbr.2023.114762.

Rio-Alamos, C., Montefusco-Siegmund, R., Cañete, T., Sotomayor, J., & Fernández-Teruel A. (2023). Acute Relaxation Response Induced by Tibetan Singing Bowl Sounds: A Randomized Controlled Trial. European Journal of Investigation in Health, Psychology and Education, 13(2),317-330. https://doi.org/10.3390/ejihpe13020024

Sampedro-Viana, D., Cañete, T., Sanna, F., Oliveras, I., Lavín, V., Torrecilla, P., Río-Álamos, C., Tapias-Espinosa, C., Sánchez-González, A., Tobeña, A., & Fernández-Teruel, A. (2023). Atypical antipsychotics attenuate MK801-induced social withdrawal and hyperlocomotion in the RHA rat model of schizophrenia-relevant features. Psychopharmacology, 240(9), 1931-1945. https://doi.org/10.1007/s00213-023-06411-w

Sampedro-Viana, D., Cañete, T., Sanna, F., Oliveras, I., Castillo-Ruiz, M., Corda, MG., Giorgi, O., Tobeña, A., & Fernández-Teruel, A. (2023). c-Fos expression after neonatal handling in social brain regions: Distinctive profile of RHA-rat schizophrenia model on a social preference test. Behavioural Brain Research, 453:114625. https://doi.org/10.1016/j.bbr.2023.114625

Sampedro-Viana, D., Cañete, T., Mourelo, L., Oliveras, I., Peralta-Vallejo, N., Tobeña, A., & Fernández-Teruel, A. (2023). Low prepulse inhibition predicts lower social interaction, impaired spatial working memory, reference memory and cognitive flexibility in genetically heterogeneous rats. Physiology & Behavior, 271:114355. https://doi.org/10.1016/j.physbeh.2023.114355

Serra, M. P., Sanna, F., Boi, M., Trucas, M., Fernández-Teruel, A., Corda, M. G., Giorgi, O., & Quartu, M. (2023). Effects of Tail Pinch on BDNF and trkB Expression in the Hippocampus of Roman Low- (RLA) and High-Avoidance (RHA) Rats. International Journal of Molecular Sciences, 24(11):9498. https://doi.org/10.3390/ijms24119498

Sønderstrup, M., Batiuk, M. Y., Mantas, P., Tapias-Espinosa, C., Oliveras, I., Cañete, T., Sampedro Viana, D., Brudek, T., Rydbirk, R., Khodosevich, K., Fernández-Teruel, A., Elfving, B., & Aznar, S. (2023). A maturational shift in the frontal cortex synaptic transcriptional landscape underlies schizophrenia-relevant behavioural traits: A congenital rat model. European Neuropsychopharmacology, 74, 32-46. Https://doi.org/10.1016/j.euroneuro.2023.05.001

Tapias-Espinosa, C., Sánchez-González, A., Cañete, T., Sampedro-Viana, D., Castillo-Ruiz, MDM., Oliveras, I., Tobeña, A., Aznar, S., & Fernández-Teruel, A. (2023). Decreased activation of parvalbumin interneurons in the medial prefrontal cortex in intact inbred Roman rats with schizophrenia-like reduced sensorimotor gating. Behavioural Brain Research, 437:114113. https://doi.org/10.1016/j.bbr.2022.114113

2022

Fernández-Teruel A. (2022). From inhibition of GABA-A receptor-mediated transmission by conventional antidepressants to negative allosteric modulators of alpha5-GABA-A receptors as putative fast-acting antidepressant drugs: closing the circle? Current Neuropharmacology, 20(1):85-89. doi: 10.2174/1570159X19666211104144650

Fernández-Teruel A. (2022). The power of “touch” and early enriched sensory stimulation: effects on brain development, neuroregeneration and neurodegeneration in rodents and preterm human infants. Neural Regeneration Research, 17(6):1248-1250. doi:10.4103/1673-5374.327336

Oliveras, I., Soria-Ruiz, OJ., Sampedro-Viana, D., Cañete, T., Río-Álamos, C., Tobeña, A., & Fernández-Teruel, A. (2022). Different maturation patterns for sensorimotor gating and startle habituation deficits in male and female RHA vs RLA rats. Behavioural Brain Research. https://doi.org/10.1016/j.bbr.2022.114021

Oliveras I, Soria-Ruiz OJ, Sampedro-Viana D, Cañete T, Tobeña A, Fernández-Teruel A. (2022). Social preference in Roman rats: Age and sex variations relevance for modeling negative schizophrenia-like features. Physiol. Behav,247:113722. doi:10.1016/j.physbeh.2022.113722.

Oliveras I, Tapias-Espinosa C, Río-Álamos C, Sampedro-Viana D, Cañete T, Sánchez-González A, Tobeña A, Fernández-Teruel A (2022). Prepulse inhibition deficits in inbred and outbred rats and between-strain differences in startle habituation do not depend on startle reactivity levels. Behav Processes, 197:104618. doi: 10.1016/j.beproc.2022.104618

Serra, M. P., Sanna, F., Boi, M., Poddighe, L., Secci, L., Trucas, M., Fernández-Teruel, A., Corda, M. G., Giorgi, O., & Quartu, M. (2022). Acute Stress Induces Different Changes on the Expression of BDNF and trkB in the Mesocorticolimbic System of Two Lines of Rats Differing in Their Response to Stressors. International Journal of Molecular Sciences, 23. https://doi.org/10.3390/ijms232314995

Vohra HZ, Saunders JM, Jaster AM, de la Fuente Revenga M, Jimenez J, Fernández-Teruel A, Wolstenholme JT, Beardsley PM, González-Maeso J. (2022). Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice. Psychopharmacology, 239(6): 1649-1664. doi: 10.1007/s00213-021-05913-9.

2021

Fernández-Teruel, A. (2021). Conflict between Threat Sensitivity and Sensation Seeking in the Adolescent Brain: Role of the Hippocampus, and Neurobehavioural Plasticity Induced by Pleasurable Early Enriched Experience. Brain Sciences, 11. https://doi.org/10.3390/brainsci11020268

Fernández-Teruel, A., Oliveras, I., Cañete, T., Rio-Álamos, C., Tapias-Espinosa, C., Sampedro-Viana, D., Sánchez-González, A., Sanna, F., Torrubia, R., González-Maeso, J., Driscoll, P., Morón, I., Torres, C., Aznar, S., Tobeña, A., Corda, M. G., & Giorgi, O. (2021). Neurobehavioral and neurodevelopmental profiles of a heuristic genetic model of differential schizophrenia- and addiction-relevant features: The RHA vs. RLA rats. Neuroscience and Biobehavioral Reviews, 131, 597-617. https://doi.org/10.1016/j.neubiorev.2021.09.042

Sampedro Viana, D., Cañete Ramírez, A., Sanna, F., Soley, B., Giorgi, O., Corda, M. G., Torrecilla Gonzalez, P., Oliveras Puigdellivol, I., Tapias Espinosa, C., Rio-Alamos, C., Sanchez Gonzalez, A., Tobeña, A., & Fernandez Teruel, A. (2021). Decreased social interaction in the RHA rat model of schizophrenia-relevant features: Modulation by neonatal handling. Behavioural Processes, 188:104397. https://doi.org/10.1016/j.beproc.2021.104397

Sánchez-González A, Thougaard E, Tapias-Espinosa C, Cañete T, Sampedro-Viana D, Saunders JM, Toneatti R, Tobeña A, Gónzalez-Maeso J, Aznar S*, Fernández-Teruel A. (2021). Increased thin-spine density in frontal cortex pyramidal neurons in a genetic rat model of schizophrenia-relevant features. European Neuropsychopharmacology, 44: 79-91. doi: 10.1016/j.euroneuro.2021.01.006

Tapias-Espinosa, C., Cañete, T., Sampedro-Viana, D., Brudek, T., Kaihøj, A., Oliveras, I., Tobeña, A., Aznar, S., & Fernández-Teruel, A. (2021). Oxytocin attenuates schizophrenia-like reduced sensorimotor gating in outbred and inbred rats in line with strain differences in CD38 gene expression. Physiology and behavior, 240:113547. https://doi.org/10.1016/j.physbeh.2021.113547

2020

Fernández-Teruel A, Tobeña A. (2020). Revisiting the role of anxiety in the initial acquisition of two-way active avoidance: pharmacological, behavioural and neuroanatomical convergence. Neuroscience and Biobehavioral Reviews 118:739-758. doi.org/10.1016/j.neubiorev.2020.08.014

Fuentes-Verdugo E, Pellón R, Papini MR, Torres C, Fernández-Teruel A, Anselme P. (2020). Effects of partial reinforcement on autoshaping in inbred Roman high- and low-avoidance rats. Physiology & Behavior, 225:113111. doi:10.1016/j.physbeh.2020.113111.

Giorgi O, Corda MG, Fernández-Teruel A. (2020). A Genetic Model of Impulsivity, Vulnerability to Drug Abuse and Schizophrenia-Relevant Symptoms With Translational Potential: The Roman High- vs. Low-Avoidance Rats. In: Belin, D., Robbins, T. W., Hollander, E., Moreno, M., eds. (2020). Impulsive Compulsive Spectrum Disorders (Frontiers Research Topics). Lausanne: Frontiers Media SA. 176-191. doi: 10.3389/978-2-88963-991-5

Østerbøg, T. B., On, D. M., Oliveras, I., Río-Álamos, C., Sanchez-Gonzalez, A., Tapias-Espinosa, C., Tobeña, A., González-Maeso, J., Fernández-Teruel, A., & Aznar, S. (2020). Metabotropic Glutamate Receptor 2 and Dopamine Receptor 2 Gene Expression Predict Sensorimotor Gating Response in the Genetically Heterogeneous NIH-HS Rat Strain. Molecular Neurobiology, 57(3), 1516-1528. https://doi.org/10.1007/s12035-019-01829-w

Ráez, A., Oliveras, I., Río-Álamos, C., Díaz-Morán, S., Cañete, T., Blázquez, G., Tobeña, A., & Fernández-Teruel, A. (2020). A missing link between depression models: Forced swimming test, helplessness and passive coping in genetically heterogeneous NIH-HS rats. Behavioural Processes, 177:104142. https://doi.org/10.1016/j.beproc.2020.104142