{"id":62,"date":"2010-06-22T15:30:20","date_gmt":"2010-06-22T13:30:20","guid":{"rendered":"https:\/\/webs.uab.cat\/ppf\/presentacio-2\/"},"modified":"2026-09-30T18:51:40","modified_gmt":"2026-09-30T16:51:40","slug":"presentacio-2","status":"publish","type":"page","link":"https:\/\/webs.uab.cat\/ppf\/en\/presentacio-2\/","title":{"rendered":"Infraestructure and equipment"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The Fermentation Pilot Plant features more than <strong>150 m\u00b2 of specialized facilities<\/strong> equipped with advanced technologies for the development, scale-up and validation of bioprocesses.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Bioreactors and Culture Systems<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The fermentation area enables operation at different process scales and reproduction of the conditions required for efficient transfer to pilot-scale production.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Available equipment includes:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Laboratory fermenters from <strong>2 to 5 liters<\/strong>.<\/li>\n\n\n\n<li><strong>Parallel two- and three-bioreactor systems with centralized control<\/strong>, ideal for comparative studies and process optimization.<\/li>\n\n\n\n<li><strong>50-liter<\/strong> pilot fermenter.<\/li>\n\n\n\n<li><strong>250-liter<\/strong> pilot fermenter.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This configuration enables progressive scale-up strategies while maintaining control of the key process parameters.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Downstream Processing<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The facility is equipped with specialized technologies for biomass recovery, concentration and bioproduct processing.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Available technologies include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Disc-stack centrifuge with centrifugal forces up to <strong>8,800 g<\/strong>.<\/li>\n\n\n\n<li>Tubular centrifuge with centrifugal forces up to <strong>15,000 g<\/strong>.<\/li>\n\n\n\n<li><strong>30-inch cartridge filtration systems<\/strong>.<\/li>\n\n\n\n<li>Pilot-scale <strong>Tangential Flow Filtration (TFF)<\/strong> system with up to <strong>2.5 m\u00b2 membrane area<\/strong>, suitable for microfiltration, ultrafiltration and diafiltration processes.<\/li>\n\n\n\n<li>Mechanical cell disruption systems at laboratory and pilot scale for intracellular product recovery.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">This equipment enables the development and optimization of separation, concentration, purification and downstream processing operations under conditions representative of industrial environments.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Analytical Laboratory and Process Monitoring<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The facility includes analytical equipment for culture monitoring and sample characterization:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>UV-Visible spectrophotometers.<\/li>\n\n\n\n<li><strong>Y15<\/strong> biochemical analyzer.<\/li>\n\n\n\n<li>Optical microscope.<\/li>\n\n\n\n<li>Biological safety cabinet.<\/li>\n\n\n\n<li>Incubators and laboratory ovens.<\/li>\n\n\n\n<li>Supporting instrumentation for process monitoring and control.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>Molecular Biology<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The plant also provides molecular biology equipment for the development and characterization of microorganisms and cell cultures:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Electrophoresis system.<\/li>\n\n\n\n<li>PCR thermocycler.<\/li>\n\n\n\n<li>Auxiliary equipment for molecular analysis and culture monitoring.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>The Fermentation Pilot Plant features more than 150 m\u00b2 of specialized facilities equipped with advanced technologies for the development, scale-up and validation of bioprocesses. Bioreactors and Culture Systems The fermentation area enables operation at different process scales and reproduction of the conditions required for efficient transfer to pilot-scale production. Available equipment includes: This configuration enables [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-62","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/pages\/62","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/comments?post=62"}],"version-history":[{"count":3,"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/pages\/62\/revisions"}],"predecessor-version":[{"id":308,"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/pages\/62\/revisions\/308"}],"wp:attachment":[{"href":"https:\/\/webs.uab.cat\/ppf\/en\/wp-json\/wp\/v2\/media?parent=62"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}