Research at the Puig2 Lab is focused on elucidating the molecular mechanisms underlying the effects of cannabinoids in the brain under both physiological and pathological conditions. One main line of research involves studying the pharmacological effects of cannabinoids (both endocannabinoids and plant-derived) in specific mouse behaviors, particularly memory processes, and their underlying cellular and molecular effects. This research is being conducted in collaboration with Dr. Valjent (CNRS, France), Dr. Marsicano (INSERM, France), Dr. Gertsch (University of Bern, Switzerland), and Dr. Ding (Stanford University, USA).
The second main line of research is related to pathology and focuses on assessing the therapeutic effects of the non-psychoactive cannabinoid cannabidiol (CBD) in primary mitochondrial diseases. This research is being carried out in collaboration with Dr. Quintana (UAB) and Dr. Bellusci (12 de Octubre Hospital).