{"id":4,"date":"2025-03-17T10:45:48","date_gmt":"2025-03-17T08:45:48","guid":{"rendered":"https:\/\/webs.uab.cat\/reproplastic\/?page_id=4"},"modified":"2025-06-02T12:20:53","modified_gmt":"2025-06-02T10:20:53","slug":"reproplastic","status":"publish","type":"page","link":"https:\/\/webs.uab.cat\/reproplastic\/","title":{"rendered":"HOME"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<h2 class=\"wp-block-heading\">NANOPLASTICS AS EMERGING POLLUTANTS: Investigating Risks to Reproductive Health of Terrestrial Mammals<\/h2>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"634\" height=\"500\" src=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Captura-de-pantalla-2025-03-17-092815-1.jpg\" alt=\"\" class=\"wp-image-66\" srcset=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Captura-de-pantalla-2025-03-17-092815-1.jpg 634w, https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Captura-de-pantalla-2025-03-17-092815-1-300x237.jpg 300w\" sizes=\"auto, (max-width: 634px) 100vw, 634px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p class=\"has-text-align-right\"><strong>Start date<\/strong>: 01\/09\/2024<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<p><strong>End date<\/strong>: 31\/08\/2028<\/p>\n<\/div>\n<\/div>\n\n\n\n<p><strong>Project PID2023-150392OB-I00 funded by MICIU\/AEI\/ 10.13039\/501100011033 and by ERDF\/EU<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"198\" src=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Imatge1-1024x198.jpg\" alt=\"Project PID2023-150392OB-I00 funded by MICIU\/AEI\/ 10.13039\/501100011033 and by ERDF\/EU.\" class=\"wp-image-67\" srcset=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Imatge1-1024x198.jpg 1024w, https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Imatge1-300x58.jpg 300w, https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Imatge1-768x149.jpg 768w, https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Imatge1-1200x232.jpg 1200w, https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Imatge1.jpg 1298w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"91\" height=\"42\" src=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/04\/Captura-de-pantalla-2025-04-01-093810-5.jpg\" alt=\"\" class=\"wp-image-228\" style=\"width:78px;height:auto\" \/><\/figure>\n\n\n\n<p>Plastic pollution is a growing global environmental challenge. In the environment, plastics break down creating massive amounts of smaller particles: microplastics (MPLs, &lt;5 mm) and nanoplastics (NPLs, &lt;1 \u00b5m). Their widespread distribution, persistence, and small size make them highly bioavailable, raising serious concerns about their potential harmful effects on wildlife and human health. Given that reproductive function is highly sensitive to pollutants, MPLs and NPLs may impact fertility of the exposed individuals and pose risks to future generations. Nonetheless, the consequences of MPLs and NPLs exposure on mammalian reproduction remain unclear<\/p>\n\n\n\n<p>This project <strong>aims to investigate the effects of multigenerational chronic NPLs exposures on the reproductive function and fertility of terrestrial mammals<\/strong>, using the laboratory mouse as a model.<\/p>\n\n\n\n<p>Our research focuses on:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Evaluating the potential <strong>toxicological effects<\/strong> of NPLs exposure on reproductive function, including:\n<ul class=\"wp-block-list\">\n<li>Female and male gonadal function.<\/li>\n\n\n\n<li>Gametes and preimplantation embryos.<\/li>\n\n\n\n<li>Placentas and developing fetuses.<\/li>\n\n\n\n<li>Fertility of the exposed individuals.<\/li>\n<\/ul>\n<\/li>\n\n\n\n<li>Investigating the <strong>mechanisms<\/strong> <strong>of NPLs toxicity<\/strong>, particularly oxidative stress, inflammation and genotoxicity in the reproductive system.<\/li>\n\n\n\n<li>Identifying <strong>fertility<\/strong> <strong>biomarkers<\/strong> associated with NPLs exposure.<\/li>\n<\/ol>\n\n\n\n<p>This project addresses critical gaps in our understanding of NPLs&#8217; impact on mammalian reproduction. Our findings will contribute to the growing body of knowledge on the environmental and health impacts of NPLs, informing future risk assessments and policy decisions. This information will also be instrumental in developing effective biosurveillance strategies for these pervasive pollutants, including the use of biomarkers to evaluate NPLs-induced reproductive damage. A deeper understanding of NPLs\u2019 effects on reproduction may guide the development of protective and mitigative measures to reduce their impact.<\/p>\n\n\n\n<p class=\"has-text-align-center\"><em>To learn more<a href=\"https:\/\/webs.uab.cat\/reproplastic\/reproplastic\/home\/\" data-type=\"page\" data-id=\"61\">: ABOUT THE PROJECT<\/a><\/em><\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/bsky.app\/profile\/reproplastic.bsky.social\"><img loading=\"lazy\" decoding=\"async\" width=\"204\" height=\"192\" src=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/04\/baixa.png\" alt=\"\" class=\"wp-image-270\" style=\"width:48px;height:auto\" \/><\/a><\/figure>\n<\/div>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><a href=\"https:\/\/x.com\/reproplastic\"><img loading=\"lazy\" decoding=\"async\" width=\"346\" height=\"145\" src=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/06\/baixa.png\" alt=\"\" class=\"wp-image-357\" style=\"width:106px;height:auto\" srcset=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/06\/baixa.png 346w, https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/06\/baixa-300x126.png 300w\" sizes=\"auto, (max-width: 346px) 100vw, 346px\" \/><\/a><\/figure>\n<\/div>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>NANOPLASTICS AS EMERGING POLLUTANTS: Investigating Risks to Reproductive Health of Terrestrial Mammals Start date: 01\/09\/2024 End date: 31\/08\/2028 Project PID2023-150392OB-I00 funded by MICIU\/AEI\/ 10.13039\/501100011033 and by ERDF\/EU Plastic pollution is a growing global environmental challenge. In the environment, plastics break down creating massive amounts of smaller particles: microplastics (MPLs, &lt;5 mm) and nanoplastics (NPLs, &lt;1 [&hellip;]<\/p>\n","protected":false},"author":2443,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HOME - REPROPLASTIC<\/title>\n<meta name=\"description\" content=\"Logo reproplastic\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/webs.uab.cat\/reproplastic\/\" \/>\n<meta property=\"og:locale\" content=\"ca_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HOME - REPROPLASTIC\" \/>\n<meta property=\"og:description\" content=\"Logo reproplastic\" \/>\n<meta property=\"og:url\" content=\"https:\/\/webs.uab.cat\/reproplastic\/\" \/>\n<meta property=\"og:site_name\" content=\"REPROPLASTIC\" \/>\n<meta property=\"article:modified_time\" content=\"2025-06-02T10:20:53+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/webs.uab.cat\/reproplastic\/wp-content\/uploads\/sites\/648\/2025\/03\/Captura-de-pantalla-2025-03-17-092815-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"634\" \/>\n\t<meta property=\"og:image:height\" content=\"500\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Temps estimat de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minuts\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/webs.uab.cat\/reproplastic\/\",\"url\":\"https:\/\/webs.uab.cat\/reproplastic\/\",\"name\":\"HOME - 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