{"id":152,"date":"2024-02-21T12:13:14","date_gmt":"2024-02-21T10:13:14","guid":{"rendered":"https:\/\/webs.uab.cat\/therCNS\/?page_id=152"},"modified":"2026-03-18T16:04:21","modified_gmt":"2026-03-18T14:04:21","slug":"publications-last-5-years-m","status":"publish","type":"page","link":"https:\/\/webs.uab.cat\/therCNS\/publications-last-5-years-m\/","title":{"rendered":"Publications (Last 5 years)"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><strong><mark style=\"background-color:var(--color-blanc);color:var(--color-marca-primari)\" class=\"has-inline-color\">2026<\/mark><\/strong>\u00a0<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>R. Blanch; J. Esandi; R. Guerrero-Yag\u00fce; J. del Rey; J. Roig-Soriano; A. Lleo; E. Carro; N. Mestre-Franc\u00e9s; G. Devau; I. Ferrer; A. Meseguer; JL. Lanciego; B. Almolda; A. Bosch; M. Chill\u00f3n (2026). Long-term effects of s-KL treatment in wild-type mice, enhancing longevity, physical well-being, and neurological resilience. <em>Genes and Diseases<\/em>. in press.<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Chocarro J, Marana S, Espelosin M, Rico AJ, Ariznabarreta G, Lorenzo-Ramos E, Ilarduya MM, Hernandez-Alcoceba R, Chill\u00f3n M, Vila M, Kordower JH, Schapira AHV, Garcia-Osta A, Cuadrado-Tejedor MDM, Lanciego JL. (2026). Introducing PIGMO, a novel PIGmented MOuse model of Parkinson&#8217;s disease. <em>NPJ Parkinson&#8217;s Disease<\/em>. Feb 11. <a href=\"10.1038\/s41531-026-01289-9\">doi: 10.1038\/s41531-026-01289-9<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Muscolino E, Puig-Torrents M, Buigues Bisquert J, Correa Mendonca D, Tall\u00f3-Parra M, Perez-Vilaro G, Ca\u00f1o-Prades O, Meehan GR, Kerr K, Herder V, Chill\u00f3n M, Castello A, Sanjuan R, Patel AH, D\u00edez J. (2026). Coronaviruses reprogram the tRNA epitranscriptome to favor viral protein expression. <em>Nature Communication<\/em>. Feb 19. <a href=\"10.1038\/s41467-026-69700-w\">doi: 10.1038\/s41467-026-69700-w<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><mark style=\"background-color:var(--color-blanc);color:var(--color-marca-primari)\" class=\"has-inline-color\">2025<\/mark><\/strong>\u00a0<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>A. Brao, A. S\u00e1nchez, I. Rodr\u00edguez J. del Rey,Silvia Lope-Piedrafita, E. Prat, V. Nunes, M. Chill\u00f3n, R. Est\u00e9vez, and A. Bosch. (2025). Gene therapy rescues brain edema and motor function in a mouse model of megalencephalic leukoencephalopathy with subcortical cysts. <em>Molecular Therapy<\/em>. 33(4):1434-1448. <a href=\"http:\/\/10.1016\/j.ymthe.2025.02.046\">doi: 10.1016\/j.ymthe.2025.02.046 <\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Roig-Soriano J, Edo A, Verd\u00e9s S, Mart\u00edn-Alonso C, S\u00e1nchez-de-Diego C, Rodriguez-Estevez L, Serrano AL, Abraham CR, Bosch A, Ventura F, Jordan BA, Mu\u00f1oz-C\u00e1noves P; Chill\u00f3n M. (2025). Long-term effects of s-KL treatment in wild-type mice, enhancing longevity, physical well-being, and neurological resilience. <em>Molecular Therapy<\/em>. 33(4):1449-1465. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39988871\/\">doi: 10.1016\/j.ymthe.2025.02.030<\/a><\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>J. Esandi; P. Renault; M. Dolores Capilla-L\u00f3pez; R. Blanch; A. Edo; D. Ramirez-Gomez; A. Bosch; B. Almolda; C.A. Saura; J. Giraldo; M. Chill\u00f3n. (2025). HEBE: a novel chimeric chronokine for ameliorating memory deficits in Alzheimer\u2019s disease. <em>Biomedicine and Pharmacotherapy<\/em>. Feb:183:117815. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39818099\/\">doi: 10.1016\/j.biopha.2025.117815<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><mark style=\"background-color:var(--color-blanc);color:var(--color-marca-primari)\" class=\"has-inline-color\">2024<\/mark><\/strong>&nbsp;<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ciudad CJ, Valiuska S, Rojas JM, Nogales-Altozano P, Avi\u00f1\u00f3 A, Eritja R, Chill\u00f3n M, Sevilla N, No\u00e9 V. (2024). Polypurine Reverse Hoogsteen hairpins as a therapeutic tool for SARS-CoV-2 infection. <em>J Biol Chem. <\/em>Oct 10:107884. <a href=\"https:\/\/www.jbc.org\/article\/S0021-9258(24)02386-X\/fulltext\">doi: 10.1016\/j.jbc.2024.107884<\/a><\/li>\n\n\n\n<li>Bunuales M, Garduno A, Chillon M, Bosch A, Gonzalez-Aparicio M, Espelosin M, Garcia-Gomara M, Rico A.J, Garcia-Osta A, Cuadrado-Tejedor M, Lanciego J.L, Hernandez-Alcoceba R. (2024). Characterization of brain transduction capability of a BBB-penetrant AAV vector in mice, rats and macaques reveals differences in expression profiles. <em>Gene Therapy<\/em>. Sep;31(9-10):455-466. <a href=\"https:\/\/www.nature.com\/articles\/s41434-024-00466-w\">doi.org\/10.1038\/s41434-024-00466-w<\/a><\/li>\n\n\n\n<li>Fitzgerald M.Q, Chu T, Puppo F, Blanch R, Chill\u00f3n M, Subramaniam S, Muotri A. (2024). Protocol for Generation of Semi-guided Cortical Organoids with Complex Neural Oscillations. <em>Nature Protocols<\/em>. Sep;19(9):2712-2738. <a href=\"https:\/\/www.nature.com\/articles\/s41596-024-00994-0\">doi.org\/10.1038\/s41596-024-00994-0<\/a><\/li>\n\n\n\n<li>Favaro MTP, Alamo P, Roher N, Chillon M, Lascorz J, M\u00e1rquez M, Corchero JL, Mendoza R, Mart\u00ednez-Torr\u00f3 C, Ferrer-Miralles N, Ferreira LCS, Mangues R, V\u00e1zquez E, Parlad\u00e9 E, Villaverde A. (2024). Adjuvant-free microscale granules made of the SARS-CoV-2 spike protein trigger an anti-virus neutralizing response. <em>ACS Materials Letters<\/em>, 6:954-962. <a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acsmaterialslett.3c01643\">doi.org\/10.1021\/acsmaterialslett.3c01643<\/a><\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><mark style=\"background-color:var(--color-blanc);color:var(--color-marca-primari)\" class=\"has-inline-color\">2023<\/mark><\/strong>&nbsp;<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Roig-Soriano, J., S\u00e1nchez-de-Diego, C., Esandi-Jauregui, J., Verd\u00e9s, S., Abraham, C. R., Bosch A, Ventura, F., Chillon M (2023).\u202fDifferential toxicity profile of secreted and processed \u03b1-Klotho expression over mineral metabolism and bone microstructure.\u202f<em>Scientific Reports<\/em>,\u202f13(1):4211.\u202f<a href=\"https:\/\/doi.org\/10.1038\/s41598-023-31117-6\" target=\"_blank\" rel=\"noreferrer noopener\">doi.org\/10.1038\/s41598-023-31117-6<\/a>&nbsp;<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><mark style=\"background-color:var(--color-blanc);color:var(--color-marca-primari)\" class=\"has-inline-color\">2022<\/mark><\/strong>&nbsp;<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Leal-Juli\u00e0 M, Vilches J, Onieva A, Verd\u00e9s S, S\u00e1nchez A, Chill\u00f3n M, Navarro X, Bosch A. Proteomic quantitative study of dorsal root ganglia and sciatic nerve in type 2 diabetic mice. <em>Molecular Metabolism<\/em> (2022), 55: 101408. <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2212877821002660?via%3Dihub\" data-type=\"link\" data-id=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2212877821002660?via%3Dihub\">doi.org\/10.1016\/j.molmet.2021.101408<\/a>.&nbsp;<\/li>\n\n\n\n<li>Edo, \u00c1., Calvo-Barreiro, L., Eixarch, H., Bosch, A., Chill\u00f3n, M., &amp; Espejo, C. (2022).\u202fTherapeutic Effect of IL-21 Blockage by Gene Therapy in Experimental Autoimmune Encephalomyelitis.\u202f<em>Neurotherapeutics<\/em>,\u202f<em>19<\/em>(5), 1617-1633.\u202f<a href=\"https:\/\/doi.org\/10.1007\/s13311-022-01279-8\" target=\"_blank\" rel=\"noreferrer noopener\">doi.org\/10.1007\/s13311-022-01279-8<\/a>&nbsp;<\/li>\n\n\n\n<li>Roig-Soriano, J., Gri\u00f1\u00e1n-Ferr\u00e9, C., Espinosa-Parrilla, J. F., Abraham, C. R., Bosch, A., Pall\u00e0s, M., &amp; Chill\u00f3n, M.\u202f(2022).\u202fAAV-mediated expression of secreted and transmembrane \u03b1Klotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice.\u202f<em>Aging Cell<\/em>,\u202f<em>21<\/em>(4), Article e13581.\u202f<a href=\"https:\/\/doi.org\/10.1111\/acel.13581\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1111\/acel.13581<\/a>&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\"><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><\/ul>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2026\u00a0 2025\u00a0 2024&nbsp; 2023&nbsp; 2022&nbsp;<\/p>\n","protected":false},"author":2848,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-152","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages\/152","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/users\/2848"}],"replies":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/comments?post=152"}],"version-history":[{"count":27,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages\/152\/revisions"}],"predecessor-version":[{"id":1355,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages\/152\/revisions\/1355"}],"wp:attachment":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/media?parent=152"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}