{"id":271,"date":"2024-02-21T14:53:40","date_gmt":"2024-02-21T12:53:40","guid":{"rendered":"https:\/\/webs.uab.cat\/therCNS\/?page_id=271"},"modified":"2024-03-21T12:05:49","modified_gmt":"2024-03-21T10:05:49","slug":"home-m","status":"publish","type":"page","link":"https:\/\/webs.uab.cat\/therCNS\/home-m\/","title":{"rendered":"Miguel Chill\u00f3n’s Group (GT4CNS)"},"content":{"rendered":"\n

“Pioneering Efficient and Safe Advanced Therapies<\/em>“<\/p>\n\n\n\n

\n
\n

Our research group <\/strong>“Gene Therapy for Central Nervous System (GT4CNS)” is focused on<\/strong> the study of the molecular mechanisms involved in genetic diseases that cause nervous system dysfunction, with the final goal of developing effective and safe gene therapy strategies <\/strong>for those diseases. <\/p>\n<\/blockquote>\n<\/div><\/div>\n\n\n\n

By applying state-of-the-art techniques such as 2D and 3D cultures of iPSC-derived neurons from patients, in vivo gene therapy strategies in animal models (including transgenic models), -omic analysis (transcriptomic and spatial transcriptomic analysis), novel viral vectors, etc, our laboratory has three major complementary strategic research lines<\/strong>:<\/p>\n\n\n\n

\n
\n
\n
\"\"
Natural and chimeric chronokines to treat age-associated disorders<\/a><\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
\n
\"\"
AAV gene therapy strategies for rare diseases affecting the CNS<\/a><\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
\n
\"\"
Design, generation and production of AAV and adenovirus vectors<\/a><\/figcaption><\/figure>\n<\/div><\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

History<\/strong>. Our group was established in 2001 at the Biochemistry and Molecular Biology Department of the Universitat Aut\u00f2noma de Barcelona (UAB) and is located on the 5th floor (H-Building) of the Institute of Neurosciences at UAB. Currently, it comprises a Research Lab and a Technological Platform (UPV) for Viral Vector Production, forming the UAB-VHIR Joint Unit. This Unit is affiliated with both the Universitat Aut\u00f2noma de Barcelona and the Vall d’Hebron Research Institute (Barcelona).<\/p>\n","protected":false},"excerpt":{"rendered":"

“Pioneering Efficient and Safe Advanced Therapies“ Our research group “Gene Therapy for Central Nervous System (GT4CNS)” is focused on the study of the molecular mechanisms involved in genetic diseases that cause nervous system dysfunction, with the final goal of developing effective and safe gene therapy strategies for those diseases. By applying state-of-the-art techniques such as […]<\/p>\n","protected":false},"author":2848,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-271","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages\/271","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/users\/2848"}],"replies":[{"embeddable":true,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/comments?post=271"}],"version-history":[{"count":52,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages\/271\/revisions"}],"predecessor-version":[{"id":951,"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/pages\/271\/revisions\/951"}],"wp:attachment":[{"href":"https:\/\/webs.uab.cat\/therCNS\/wp-json\/wp\/v2\/media?parent=271"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}