In the UMPiC we carry out own research lines focused principally in neuropathology, dermatopathology, tissular regeneration and scaring and carcinogenesis among others. We are open to collaborate with other research groups.

The most relevant publications of the last 5 years.


Sandra Guallar-Garrido, Víctor Campo-Pérez, Míriam Pérez-Trujillo, Cecilia Cabrera, Jordi Senserrich, Alejandro Sánchez-Chardi, Rosa Maria Rabanal, Elisabet Gómez-Mora, Estela Noguera-Ortega, Marina Luquin and Esther Julián. (2022) Mycobacterial surface characters remodeled by growth conditions drive different tumor-infiltrating cells and IFN-g/IL-17 release in bladder cancer treatment. OncoImmunology, 2002 11:1, 2051845, DOI: 10.1080/2162402X.2022.2051845

Moreno-Gonzalez I, Edwards G 3rd, Morales R, Duran-Aniotz C, Escobedo G Jr, Marquez M, Pumarola M, Soto C. Aged Cattle Brain Displays Alzheimer’s Disease-Like Pathology and Promotes Brain Amyloidosis in a Transgenic Animal Model. Front Aging Neurosci. 2022 Jan 31; 13:815361. doi: 10.3389/fnagi.2021.815361. eCollection 2021.PMID: 35173603

Belluco S, Marano G, Baiker K, Beineke A, Oevermann A, Seehusen F, Boracchi P, Pumarola M, Mandara MT. Standardisation of canine meningioma grading: Inter-observer agreement and recommendations for reproducible histopathologic criteria. Vet Comp Oncol. 2022 Jan 23. doi: 10.1111/vco.12802

Clinical, imaging, and histopathological characteristics of a malignant intracranial meningioma with pulmonary metàstasis in a dog. Sonia Ortiz-Nisa, Cristian de la Fuente, Fabiano Sant’Ana, Martí Pumarola, Sònia Añor. Vet Record Case Reports (Open Access). April 2022; e365.


Aran A, Peg V, Rabanal RM, Bernado C, Zamora E, Molina E, Arribas YA, Arribas J, Pérez J, Roura-Mir C, Carrascal M, Cortés J and Martí M (2021) Epstein–Barr Virus+ B Cells in Breast Cancer Immune Response: A Case Report. Frontiers in Immunolgy. 2:761798. JIF: 7,561 (WOS) Q1 (24/162) Immunology Science

Marcó S, Haurigot V, Jaén ML, Ribera A, Sánchez V, Molas M, Garcia M, León X, Roca C, Sánchez X, Bertolin J, Pérez J, Elias G, Navarro M, Carretero A, Pumarola M, Andaluz A, Espada Y, Añor S, Bosch F. Seven-year follow-up of durability and safety of AAV CNS gene therapy for a lysosomal storage disorder in a large animal. Mol Ther Methods Clin Dev. 2021 Oct 5;23: 370-389. doi: 10.1016/j.omtm.2021.09.017.

Yeste N, Gómez N, Vázquez-Gómez M, García-Contreras C, Pumarola M, González-Bulnes A, Bassols A. Polyphenols and IUGR Pregnancies: Intrauterine Growth Restriction and Hydroxytyrosol Affect the Development and Neurotransmitter Profile of the Hippocampus in a Pig Model. Antioxidants (Basel). 2021 Sep 22;10(10):1505. doi: 10.3390/antiox10101505.

Ororbia A, Sanz A, Novellas R, Pastor J, Pumarola M, Fresno L, Espada Y. Diagnostic imaging and pathological findings of an abdominal mesenteric granular cell tumour in a dog. Vet Med Sci. 2021 Sep;7(5):1514-1517. doi: 10.1002/vms3.543.

Sant’Ana FJF, Omaña M, Blasco E, Pumarola M. Glial Response and Neuroinflammation in Cerebrocortical Atrophy in a Young Irish Wolfhound Dog. Animals (Basel). 2021 Jan 11;11(1):143. doi: 10.3390/ani11010143.

José-López R, Gutierrez-Quintana R, de la Fuente C, Manzanilla EG, Suñol A, Pi Castro D, Añor S, Sánchez-Masian D, Fernández-Flores F, Ricci E, Marioni-Henry K, Mascort J, Matiasek LA, Matiasek K, Brenan PM, Pumarola M. Clinical features, diagnosis, and survival analysis of dogs with glioma. J Vet Intern Med. 2021 Jul;35(4):1902-1917. doi: 10.1111/jvim.16199. Epub 2021 Jun 12.

Suñol A, Pumarola MPathology in Practice. J Am Vet Med Assoc. 2021 Nov 15;259(10):1111-1113. doi: 10.2460/javma.19.05.0227.PMID: 34727082 

Álvarez P, Blasco E, Pumarola M, Wessmann A. Aquaporin-4 protein expression in normal canine brains. BMC Vet Res. 2021 Jan 18;17(1):29. doi: 10.1186/s12917-021-02745-9.

Marín B, Otero A, Lugan S, Espinosa JC, Marín-Moreno A, Vidal E, Hedman C, Romero A, Pumarola M, Badiola JJ, Torres JM, Andréoletti O, Bolea R. Classical BSE prions emerge from asymptomatic pigs challenged with atypical/Nor98 scrapie. Sci Rep. 2021 Aug 31;11(1):17428. doi: 10.1038/s41598-021-96818-2.

Barrio T, Vidal E, Betancor M, Otero A, Martín-Burriel I, Monzón M, Monleón E, Pumarola M, Badiola JJ, Bolea R. Evidence of p75 Neurotrophin Receptor Involvement in the Central Nervous System Pathogenesis of Classical Scrapie in Sheep and a Transgenic Mouse Model. Int J Mol Sci. 2021 Mar 8;22(5):2714. doi: 10.3390/ijms22052714.


Bach-Griera M, Campo-Pérez V, Barbosa, Traserra S, Guallar-Garrido S, Moya-Andérico L, Herrero-Abadía P, Luquin M, Rabanal RM, Torrents E & Julián E. Mycolicibacterium brumae is a safe and non-toxic immunomodulatory agent for cancer treatment. Vaccines. 2020, 8, 2, 198

Wu S, Calero-Pérez P, Villamañan L, Arias-Ramos N, Pumarola M, Ortega-Martorell S, Julià-Sapé M, Arús C, Candiota AP. Anti-tumour immune response in GL261 glioblastoma generated by Temozolomide Immune-Enhancing Metronomic Schedule monitored with MRSI-based nosological images. NMR Biomed. 2020, 33 (4)

Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martín-Ibáñez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, García-Torralba A, Pascual M, Pumarola M, Alberch J, Ginés S, Martín ED, Segovia J, Soriano E, Canals JM. Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020, 323:113095.

Pi D, José-López R, Fernández F, Rabanal R, Mandara MT, Arús C, and Pumarola M. Expression of FOXP3 in Canine Gliomas:Immunohistochemical Study of Tumor-Infiltrating Regulatory Lymphocytes. J Neuropathol Exp Neurol, 2020, 79, 2:184–193

Mesa-Sánchez I, Jolly-Frahija IT, Sánchez-González K, Pumarola-Batlle M, Cervera-Castellanosa V and Ródenas S. Canine systemic mycosis associated with Chaetomium globosumin a dog. Aust Vet J, 2020

López Betran M, Mascort J, Pumarola M, Montoliu P. Cerebellar granuloprival and trans-synaptic degeneration in a Chihuahua. Veterinary Record Case Reports, 20202, 8 1

Bardagi M, Monaco M & Fondevila D. Sterile or nonantibiotic-responsive pustular dermatitis and canine leishmaniosis: a 14-case series description and a statistical association study on 2420 cases. Veterinary Dermatology (2020) 31(3): 197; (12pag) DOI: 10.1111/vde.12828

Raurell X, Centellas C, Feliz G, Almeida Francisca, Zamora A and Pumarola M. Intraventricular Tension Pneumocephalus and Pneumorrhachis in a Dog; Diagnosis, Treatment, and MRI Follow-Up. Acta Scientific Veterinary Sciences, 2020, 2.3: 01-04

Vidal E, Fernández-Borges N, Eraña H, Parra3 B, Pintado B, Sánchez-Martín MA, Charco JM, Ordóñez M, Pérez-Castro MA, Pumarola M, Mathiason CK, Mayoral T, Castilla J. Dogs are resistant to prion infection, due to the presence of asparagine at position 163 of their prion protein. The FASEB Journal. 2020; 34:3969-3982


Huor A, Espinosa JC, Vidal E, Cassard H, Douet JY, Lugan S, Aron N, Marín-Moreno A, Lorenzo P, Aguilar-Calvo P, Badiola J, Bolea R, Pumarola M, Benestad SL, Orge L, Thackray AM, Bujdoso R, Torres JM, Andreoletti O. The emergence of classical BSE from atypical/Nor98 scrapie. Proc Natl Acad Sci U S A. 2019, 116(52):26853-62

Whittemore K, Derevyanko A, Martinez P, Serrano R, Pumarola M, Bosch F, Blasco MA. Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice. Aging (Albany NY). 2019, 11(10):2916-2948

Recio A, de la Fuente C, Pumarola M, Espada Y, Añor S. Magnetic resonance imaging and computed tomographic characteristics of a glioma causing calvarial erosion in a dog. Veterinary Radiology and Ultrasound, 2019, 60(1), E1-E5

Dias S, Fernández-Flores F, Pumarola M, Recio A, Novellas R, Martorell J. Multifocal embryonal tumor in the central nervous system of a ferret (Mustela putorius furo) Journal of Exotic Pet Medicine, 2019, 28:185-192

Farré Mariné A, Borrego JF, Pumarola M, Luján Feliu-Pascual A. What Is Your Neurologic Diagnosis? J Am Vet Med Assoc. 2019, 255(7):789-792

Álvarez P, Wessmann A, Pascual M, Comas O, Pi D, Pumarola M. Cerebral gliosarcoma with perivascular involvement in a cat. JFMS Open Rep. 2019, 5(2): 2055116919879783

Ewertowska E, Andaluz A, Moll X, Aguilar A, Garcia  F, Fondevila D, Quesada R, Trujillo M, Burdío F, Berjano E. Development of a catheter-based technique for endoluminal radiofrequency sealing of pancreatic duct. International Journal of Hyperthermia (2019) 36:1;677-686; doi.10.1080/02656736.2019.1627585

Andaluz A, Ewertowska E, Moll X, Aguilar A, Garcia F, Fondevila D, Quesada R, Trujillo M,  Berjano E, Grande L, Burdío F. Endoluminal radiofrequency ablation of the main pancreatic duct is a secure and effective method to produce pancreatic atrophy and to achieve stump closure. Scientific Reports (2019), 9: Article N. 5928. doi: 10.1038/s41598-019-42411-7

Lima T. Ordeix L & Fondevila D. Possible drug-induced follicular mucinosis in a dog. Veterinary Record Case Reports (2019) May: 7(2) – e000811 (4 pag.); DOI: 10.1136/vetreccr-2019-000811. On line 2052-6121


Puigdemont A, Furiani N, De Lucia M, Carrasco I, Ordeix L, Fondevila D, Ramió-Lluch L, Brazis P. Topical polyhydroxy acid treatment for autosomal recessive congenital ichthyosis in the golden retriever: a prospective pilot study. Vet Dermatol. 2018. doi: 10.1111/vde.12654

Fernández-Flores F, García-Verdugo JM, Martín-Ibáñez R, Herranz C, Fondevila D, Canals JM, Arús C, Pumarola M. Characterization of the canine rostral ventricular-subventricular zone: Morphological, immunohistochemical, ultrastructural and neurosphere assay studies. J Comp Neurol. 2018, 526(4):721-74

Samarani F, de la Fuente C, Parodi A, Mandara MT, Pumarola M, Añor S. Immunohistochemical expression of cyclooxygenase-2 (COX-2) is not associated with tumor grade in feline meningiomas. Vet J. 2018, 241:20-23

Noguera-Ortega E, Rabanal RM, Gómez-Mora E, Cabrera C, Luquin M & Julián E. Intravesical Mycobacterium brumae triggers both local and systemic immunotherapeutic responses against bladder cancer in mice. Scientific Reports. 2018, 8, 15102

Ros C, Fernández-Flores F, de la Fuente C, Pi D, Añor S, Planellas M, Pumarola M. Tumour-to-Tumour Metastasis Phenomenon: Metastatic Prostatic Adenocarcinoma within an Anaplastic Oligodendroglioma in the Brain of a Dog. J Comp Pathol. 2018, 165:62-66

Castellví Q, Mercadal B, Moll X, Fondevila D, Andaluz A, Ivorra A. Avoiding neuromuscular stimulation in liver irreversible electroporation using radiofrequency electric fields Physics in Medicine and Biology, (2018) Jan 31; 63(3) N.03502; doi: 10.1088/1361-6560/aaa16f

Di Matti D, Fondevila D, Abramo F,  Fondati A. Aretrospective histopathological, immunohistochemical and molecular study on the presence of Leishmania spp. in the skin of cats with head and neck ulcerative dermatitis. Veterinary Dermatology, 2018 Jun;29(3):212-e76. doi: 10.1111/vde.12535