A la UMPiC duem a terme les nostres pròpies línies de recerca enfocades principalment a la neuropatologia, regeneració i cicatrització tissular i carcinogènesi entre d’altres. Des de la UPMiC estem oberts a establir col·laboracions.
Publicacions més rellevants dels darrers 5 anys.
Serrano L, Martínez-Redondo P, Marazuela-Duque A, Vazquez BN, Dooley SJ, Voigt P, Beck DB, Kane-Goldsmith N, Tong Q, Rabanal RM, Fondevila D, Muñoz P, Krüger M, Tischfield JA, Vaquero A. The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation. Gene. Dev. 2013 27(6):639-53.
V. Haurigot, S. Marcó, A. Ribera, M. García, A. Ruzo, P. Villacampa, E. Ayuso , S. Añor, A. Andaluz, M. Pineda, G. García Fructoso, M. Molas, L. Maggioni, S. Muñoz, S. Motas, J. Ruberte, F. Mingozzi, M. Pumarola & F. Bosch. Whole-body correction of mucopolysaccharidosis IIIa by intracerebrospinal fluid gene therapy. J Clin Invest. 2013, Jul 1. pii: 66778. doi: 10.1172/JCI66778. [Epub ahead of print]
Mandara MT, Fabriani E, Pavone S, Pumarola M. Feline cutaneous nerve sheath tumours: histological features and immunohistochemical evaluations. Res Vet Sci. 2013 Oct;95(2):548-55.
De Nevi E, Marco-Salazar P, Fondevila D, Blasco E, Pérez L, Pumarola M. Immunohistochemical study of doublecortin and nucleostemin in canine brain Eur J Histochem. 2013 Mar 20;57(1):e9.
Vidal E, Fernández-Borges N, Pintado B, Ordóñez M, Márquez M, Fondevila D, Torres JM, Pumarola M, Castilla J. Bovine spongiform encephalopathy induces misfolding of alleged prion-resistant species cellular prion protein without altering its pathobiological features. J Neurosci. 2013 May 1;33(18):7778-86.
Vidal E, Tortosa R, Marco P, Fondevila D, Rabanal RM, Torres JM, Pumarola M. Late stage cathepsin C, CXCL13 and Ki-67 overexpression correlate with regional neuropathology in a BSE transgenic murine model. J Comp Pathol. 2013 Jan;148(1):22-32 .
Huska J, Gaitero L, Snyman HN, Foster RA, Pumarola M, Rodenas S. Cerebellar granuloprival degeneration in an australian kelpie and a labrador retriever dog Can Vet J 2013 Jan;54(1):55-60.
Filali H, Vidal E, Bolea R, Márquez M, Marco P, Vargas A, Pumarola M, Martin-Burriel I, Badiola JJ. Gene and protein patterns of potential prion-related markers in the central nervous system of clinical and preclinical infected sheep. Vet Res. 2013 Mar 11;44(1):14
Márquez M., Pedregosa JR, López J, Marco-Salazar P, Fondevila D, Pumarola, M. Leishmania amastigotes in the central nervous system of a naturally infected dog J Vet Diagn Invest. 25(1) January 2013.
Ortega-Martorell S, Lisboa PJ, Vellido A, Simões RV, Pumarola M, Julià-Sapé M, Arús C. Convex non-negative matrix factorization for brain tumor delimitation from mrsi data. PLoS One. 2012;7(10):e47824
Bardagí M, Fondevila D, Ferrer L. COX-2 is not expressed by canine cutaneous epitheliotropic T cell lymphoma. Vet Dermatol, N. VDE-1066, Accepted june 2012 DOI: 10.1111/j.1365-3164.2012.01066.x
De la Fuente C, Pumarola M, Ródenas S, Foradada L, Lloret A, Pérez de Val B, Añor S. Imaging diagnosis-magnetic resonance imaging findings of an intracranial epidural tuberculoma in a dog. Vet Radiol Ultrasound. 2012 Nov-Dec;53(6):655-9
Ródenas S, Pumarola M, Gopegui RR, Añor S. Bilateral Sciatic Neuropathy in Dogs Caused by Spontaneous Muscular and Intraneural Hemorrhage. J Vet Intern Med. 2012 Sep-Oct;26(5):1227-31.
Gallego X, Molas S, Amador-Arjona A, Marks MJ, Robles N, Murtra P, Armengol L, Fernández-Montes RD, Gratacòs M, Pumarola M, Cabrera R, Maldonado R, Sabrià J, Estivill X, Dierssen M. Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.. Amino Acids. 2012 Aug;43(2):897-909
S. Cerrato, Brazis, P, Meana, A, Fondevila, D, Puigdemont,A. In vitro development and characterization of canine epidermis on porcine acellular dermal matrix . Vet J. 2012 Aug;193(2):503-7.
Márquez M., Ródenas S., Molin J., Rabanal R. M., Fondevila D., Añor S., Pumarola M.. Protothecal pyogranulomatous meningoencephalitis in a dog without evidence of disseminated infection. Vet Rec. 2012 Jul 28;171(4):100.
Naranjo C., Fondevila D., Altet l, Francino O., Ríos J., Roura X, Peña X. Evaluation of the presence of Leishmania spp. by real-time PCR in the lacrimal glands of dogs with leishmaniasis. Vet J. 2012 Jul;193(1):168-73. Vidal E, Tortosa R, Marco P, Fondevila D, Rabanal RM, Torres JM, Pumarola M. Late Stage Cathepsin C, CXCL13 and Ki-67 Overexpression Correlate with Regional Neuropathology in a BSE Transgenic Murine Model. J Comp Pathol. 2012 Jul 10. [Epub ahead of print]
De la Fuente C, Shelton GD, Molin J, Pumarola M, Guo LT, Añor S. Pathology in practice. Dystrophin-deficient muscular dystrophy. J Am Vet Med Assoc. 2012; 240(12): 1423-1425.
Dorcaratto D, Burdío F, Fondevila D, Andaluz A, Poves I, Martinez M, Quesada R, Berjano E, Grande L. Laparoscopic distal pancreatectomy: feasibility study of radiofrecuency assisted transection in a porcine model. J Laparoendosc Adv Surg Tech A. 2012 Apr;22(3):242-8.
Davila M, Candiota AP, Pumarola M, Arús C. Minimization of spectral pattern changes during HRMAS experiments at 37 degrees celsius by prior focused microwave irradiation. MAGMA. 2012 Jan 29. [Epub ahead of print]
U. Ibaseta-Bejarano, C.Naranjo, P.Marco-Salazar, M.Pumarola. Spongiform polioencephalopathy/spongy degeneration of the brain grey matter in a Malinois litter. Revista oficial de A.V.E.P.A 2012; 32(2): 101-104
Simões RV, Ortega-Martorell S, Delgado-Goñi T, Fur YL, Pumarola M, Candiota AP, Martín J, Stoyanova R, Cozzone PJ, Julià-Sapé M, Arús C. Improving the classification of brain tumors in mice with perturbation enhanced PE-MRSI.. Integr Biol-UK 2012; 4(2): 183-191.
Bardagí M, Fondevila D, Ferrer L. Immunohistochemical Detection of COX-2 in Feline and Canine Actinic Keratoses and Cutaneous Squamous Cell Carcinoma. J Comp Pathol. 2012 Jan;146(1):11-7.
Tortosa R, Castells X, Vidal E, Costa C, Ruiz de Villa Mdel C, Sánchez A, Barceló A, Torres JM, Pumarola M, Ariño J. Central nervous system gene expression changes in a transgenic mouse model for bovine spongiform encephalopathy. Vet Res. 2011 Oct 28;42(1):109.
Molín J, Márquez M, Raurell X, Matiasek K, Ferrer I, Pumarola M. Acute clinical onset chronic inflammatory demyelinating polyneuropathy in a dog. Muscle Nerve. 2011 Sep;44(3):441-4.
Docampo, M.J., Cabrera, J., Rabanal, R.M. Bassols,A. MMP-2, MMP-9 and MT1-MMP expression in melanocytic tumors of dogs and canine melanoma cell lines. Am J Vet Res. 2011 Aug;72(8):1087-96.
Alex Perálvarez-Marín, Francesc Sepulcre, Mercedes Márquez, Maria Grazia Proietti, Esteve Padrós. Combination of Extended X-Ray Absorption Fine Structure Spectroscopy with Lipidic Cubic Phases for the Study of Cation Binding in Bacteriorhodopsin. Eur Biophys J. 2011 Aug;40(8):1007-12
Filali H, Martin-Burriel I, Harders F, Varona L, Lyahyai J, Zaragoza P, Pumarola M, Badiola JJ, Bossers A, Bolea R. Gene Expression Profiling and Association with Prion-Related Lesions in the Medulla Oblongata of Symptomatic Natural Scrapie Animals. PLoS One. 2011;6(5):e19909. Epub 2011 May 24.
Bardagi M. Montoliu P, Ferrer L, Fondevila D, Pumarola M. Acral Mutilation Syndrome in a Miniature Pinscher. J Comp Pathol. 2011 Feb-Apr;144(2-3):235-8
Ródenas S, Pumarola M, Gaitero L, Zamora A, Añor S. Magnetic resonance imaging findings in 40 dogs with histologically confirmed intracranial tumours. Vet J. 2011 Jan;187(1):85-91
Domange C, Casteignau A, Collignon G, Pumarola M, Priymenko N. Longitudinal study of Australian stringhalt cases in France. J Anim Physiol Anim Nutr (Berl). 2010 Dec;94(6):712-20
Millán Y, Mascort J, Blanco A, Costa C, Masian D, Guil-Luna S, Pumarola M, Martin de Las Mulas J. Hypomielination in three Weimaraner dogs. J Small Anim Pract. 2010 Nov;51(11):594-8 Viu J, Armengou L, Jose-Cunilleras E, Cesarini C, Pumarola M, Monreal L. Cranioencephalic malformation with atlanto-occipital luxation in an Andalusian neonate foal. J Vet Intern Med. 2010 May-Jun;24(3):639-42.
Serafin, A Molín J, Márquez M, Blasco E, Vidal E, Foradada L, Añor S, Rabanal RM, Fondevila D, Bosch F, Pumarola M. Diabetic neuropathy: electrophysiological and morphological study of peripheral nerve degeneration and regeneration in transgenic mice expressing IFNß in ß cells. Muscle Nerve. 2010 May;41(5):630-41
Márquez M, Pérez L, Serafín A, Teijeira S, Navarro C, Pumarola M. Characterisation of Lafora-like bodies and other polyglucosan bodies in two aged dogs with neurological disease. Vet J. 2010 Feb;183(2):222-5.
Capucchio MT, Márquez M, Pregel P, Foradada L, Bravo M, Mattutino G, Torre C, Schiffer D, Catalano D, Valenza F, Guarda F, Pumarola M. Parenchymal and vascular lesions in ageing equine brains: histological and immunohistochemical studies. J Comp Pathol. 2010 Jan;142(1):61-73.
Bolea R, Vidal E, Marín B, Márquez M, Vargas A, Pumarola M, Badiola JJ. Rapid chromatographic immunoassay study of brain PrPsc distribution in classical scrapie. J Vet Diagn Invest. 2010 Jan;22(1):82-5.
M Pumarola. L’Acadèmia: Origen i creació. Dins: AA.VV. 50 aniversari 1960-2010. Barcelona: Acadèmia de Ciències Veterinàries de Catalunya; 2010. p. 146-149
R Bolea, I Martin-Burriel, MC Garza, M Pumarola. Patogenia i transmisión. Dins: J.J. Badiola Díez, M. Pumarola i Batlle. Encefalopatías Espongiformes Transmisibles. 1 ed. Barcelona: MAYO Ediciones; 2010. p. 33-47
R Bolea, I Martin-Burriel, MC Garza, M Pumarola. Patogènia i transmissió. Dins: Márquez, Mercedes; Vidal, Enric. Encefalopaties espongiformes transmissibles. Barcelona: Ediciones Mayo S.A; 2010. p. 1-1
Costa, C.; Tortosa, R.; Vidal, E.; Padilla, D.; Torres, J.M.; Ferrer, I.; Pumarola, M.; Bassols, A. Central nervous system extracellular matrix changes in a transgenic mouse model of bovine spongiform encephalopathy. Vet J. 2009 Nov;182(2):306-14
Rodriguez-Cariño, C.; Fondevila, D.; Segalés, J.; Rabanal, R.M. Expression of Kit Receptor in Feline Cutaneous Mast Cell Tumors. Vet Pathol. 2009 Sep;46(5):878-83.
Vidal E, Acín C, Foradada L, Monzón M, Márquez M, Monleón E, Pumarola M, Badiola JJ, Bolea R. Immunohistochemical characterisation of classical scrapie neuropathology in sheep. J Comp Pathol. 2009 Aug-Oct;141(2-3):135-46.
Abasolo I, Pujal J, Rabanal RM, Serafin A, Navarro P, Millan O, Real F. FDG-PET imaging of Ela1-myc mice reveals major biological differences between pancreatic acinar and ductal tumors. Eur J Nucl Med Mol Imaging. 2009 Jul;36(7):1156-66.
Marco I, Velarde R, López-Olvera JR, Cabezón O, Pumarola M, Lavín S. Systemic toxoplasmosis and Gram-negative sepsis in a southern chamois Rupicapra pyrenaica from the Pyrenees in northeast Spain. J Vet Diagn Invest. 2009 Mar;21(2):244-7.
Martí Ripoll, M., Palacio J.R., Rabanal R., Pumarola M. Morphology and function of immune system: An exemple of integrated teaching. Dins: Maite Martínez and Elena Añaños coord. IDES. Innovative teaching experimental and thecnological sciences and in haeth sciences. 1 ed. Cerdanyola del Vallès: 2009. p. 125-133.
Novellas R, Ruiz de Gopegui R, Domínguez E, Garcia A, Solanas L, Puig J, Rabanal R, Espada Y. Characterization of canine mammary tumours using B-mode colour and pulsed doppler ultrasonography. Veterinary Radiology and Ultrasound 2008; 49(2): 207-207.
Martí Ripoll, M., Palacio J.R., Rabanal R., Pumarola M.. Morphology and function of immune system: An exemple of integrated teaching. Dins: Maite Martínez and Elena Añaños coord. IDES. Innovative teaching experimental and thecnological sciences and in haeth sciences. 1 ed. Cerdanyola del Vallès: 2009. p. 125-133.
Maluquer de Motes C, Simon S, Grassi J, Torres JM, Pumarola M, Girones R. Assessing the presence of BSE and scrapie in slaughterhouse wastewater. J Appl Microbiol. 2008 Nov;105(5):1649-57.
Montoliu, P; Pumarola, M; Zamora, A; Espada Y; Lloret A; Añor S. Femoral mononeuropathy caused by a malignant sarcoma: Two case reports. Vet J. 2008 Nov;178(2):298-301.
Tortosa R, Vidal E, Costa C, Alamillo E, Torres JM, Ferrer I, Pumarola M.PUMAROLA. Stress response in the central nervous system of a transgenic mouse model of bovine spongiform encephalopathy. Vet J. 2008 Oct;178(1):126-9.
Ródenas S, Pumarola M, Añor S. Imaging Diagnosis-Cervical spine chondroma in a dog. Vet Radiol Ultrasound. 2008 Sep-Oct;49(5):464-6.
Vidal, E.; Márquez, M.; Raeber, A.J.; Meissner, K.; Oesch, B.; Pumarola, M.. Applicability of a rapid chromatographic immunoassay for analysis of the distribution of PrPBSE in confirmed BSE cases. Vet J. 2008 Sep;177(3):448-51
Maluquer de Motes C, Grassi J, Simon S, Herva ME, Torres JM, Pumarola M, Girones R. Excretion of BSE and scrapie prions in stools from murine models. Vet Microbiol. 2008 Sep 18;131(1-2):205-11.
Vidal E, Tortosa R, Costa C, Benavides J, Francino O, Sánchez-Robert E, Pérez V, Pumarola M. Lack of PrPsc immunostaining in intracranial ectopic lymphoid follicles in a sheep with concomitant non-suppurative encephalitis and Nor98-like atypical scrapie: A case report. Vet J. 2008 Aug;177(2):283-8.
L. Gaitero, S. AÑor, D. Fondevila, M. Pumarola. Canine Cutaneous Spindle Cell Tumours with Features of Peripheral Nerve Sheath Tumours: A Histopathological and Immunohistochemical Study. J Comp Pathol. 2008 Jul;139(1):16-23.
Márquez M, Serafin A, Fernández-Bellon H, Serrat S, Ferrer-Admetlla A, Bertranpetit J, Ferrer I, Pumarola M. Neuropathologic findings in an aged albino gorilla. Vet Pathol. 2008 Jul;45(4):531-7.
Maluquer de Motes C, Cano MJ, Torres JM, Pumarola M, Girones R. Detection and survival of prion agents in aquatic environments. Water Res. 2008 May;42(10-11):2465-72.
Vidal E, Tortosa R, Márquez M, Serafin A, Hidalgo J, Pumarola M. Infection of metallothionein 1+2 knockout mice with Rocky Mountain Laboratory scrapie. Brain Res. 2008 Feb 27;1196:140-50.
Llado E.; Gaitero L.; Pumarola M.; Saña M.. Perforations in archaeological Neolithic cattle skulls: a new methodological approximation for their study and explanation. Vet Med Zoot 2008; 43(65): 58-61