Illuminating the Dark Side of COX-2: Insights from Computational Simulations and Fluorescent Probes in Cancer Research Álex Pérez Sánchez Les ciclooxigenases són una família d’enzims que tenen un paper fonamental en la regulació de la inflamació, el dolor i la febre. en el cos humà. Hi ha dues isoformes principals de ciclooxigenases, COX-1 i COX-2, […]
Predicting the Electronic Absorption Band Shape of Azobenzene Photoswitches Simulations based on molecular dynamics coupled to excitation energy calculations were used to generate simulated absorption spectra for a family of halide derivatives of azobenzene, a family of photoswitch molecules with a weak absorption band around 400–600 nm and potential uses in living tissue. This is […]
Estudi de la conversió del leucotriè A4 a leucotrieno B4 impulsado por leucotriè A4 hidrolasa Miquel Canyelles Niño LTA4H is a bifunctional zinc metalloenzyme that converts leukotriene A4 (LTA4) into leukotriene B4 (LTB4), one of the most potent chemotactic agents involved in acute and chronic inflammatory diseases. In this reaction, LTA4H acts as an epoxide hydrolase with […]