J2IFAM 2024

Understanding COX-2 for the Design of New Cancer Drugs: Computational Study with Specific Photochromic Compounds Álex Pérez Sánchez Cyclooxygenases are a family of enzymes essential in the regulation of inflammation and other processes in the human body. There are two main isoforms, COX-1 and COX-2, with different roles and patterns of expression in tissues COX-1 […]

New Article in Angewandte Chemie International Edition

Three-Photon Infrared Stimulation of Endogenous Neuroreceptors in Vivo Rosalba Sortino, Marina Cunquero, Gustavo Castro-Olvera, Ricard Gelabert, Miquel Moreno, Fabio Riefolo, Carlo Matera, Noèlia Fernàndez-Castillo, Luca Agnetta, Michael Decker, José Maria Lluch, Jordi Hernando, Pablo Loza-Alvarez, Pau Gorostiza To interrogate neural circuits and crack their codes, in vivobrain activity imaging must be combined with spatiotemporally precise […]

EuChemS CompChem 2023

Illuminating the Dark Side of COX-2: Insights from Computational Simulations and Fluorescent Probes in Cancer Research Álex Pérez Sánchez Cyclooxygenases are a family of enzymes that play a critical role in regulating inflammation, pain, and fever in the human body. There are two main isoforms of cyclooxygenases, COX-1 and COX- 2, with different roles and […]