Separate a city from a state, province, region or country with a comma.
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Do not use a comma between the month and the year.
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In most numbers of one thousand or more, use commas between groups of three digits, counting from the right.
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Exceptions are degree temperatures, year numbers of four digits, addresses, page numbers and other uses of numbers for a non-quantifying purpose (see the subsection “Numbers and commas” in Numbers and punctuation).